The atypical cadherin Fat is a conserved regulator of planar cell polarity, but the mechanisms by which Fat controls cell shape and tissue structure are not well understood. Here, we show that Fat is required for the planar polarized organization of actin denticle precursors, adherens junction proteins and microtubules in the epidermis of the late Drosophila embryo. In wild-type embryos, spatia...

let r be a fnite commutative ring and n(r) be the set of non unit elements of r. the non unit graph of r, denoted by gamma(r), is the graph obtained by setting all the elements of n(r) to be the vertices and defning distinct vertices x and y to be adjacent if and only if x - yin n(r). in this paper, the basic properties of gamma(r) are investigated and some characterization results regarding co...

Frizzled receptors can activate two alternative signal transduction pathways: the canonical Wnt pathway or the planar cell polarity pathway. Recent studies of the Naked cuticle protein suggest a mechanism for the inactivation of the canonical pathway and concomitant activation of the planar cell polarity pathway.