BACKGROUND Epidemiological research links vitamin D status to various brain-related outcomes. However, few trials examine whether supplementation can improve such outcomes and none have examined effects on cognition. This study examined whether Vitamin D supplementation led to improvements in diverse measures of cognitive and emotional functioning, and hypothesised that supplementation would le...

BACKGROUND Depression and anxiety are prevalent serious psychiatric disorders. Several drugs are used to treat these conditions but these are often associated with serious side effects. For this reason alternative therapies, including herbal medication such as saffron, have been proposed. We aimed to assess the effects of saffron extract for the treatment of anxiety and depression using a 12-we...

One hundred forty-six volunteers were randomized to receive a placebo or an allicin-containing garlic supplement, one capsule daily, over a 12-week period between November and February. They used a five-point scale to assess their health and recorded any common cold infections and symptoms in a daily diary. The active-treatment group had significantly fewer colds than the placebo group (24 vs 6...

The aim of this work was to prepare gelatin-based hard capsule shells from natural sources, cassava starch and hibiscus leaves. effects composition between leaves, temperature on characteristic investigated. Extraction gelatinization were the main method which used in study. A different compositions leaves gel added into boiling flask for 2 h. Temperature maintained at 50, 70 100 oC. optimum re...

conclusions the ph-dependent peppermint oil capsule and lactol tablet (bacillus coagulans+ fos) as synbiotics seem to be superior to placebo in decreasing the severity, duration and frequency of pain in abdominal pain-related functional gi disorders. background still there is no consensus on the best treatment for abdominal pain-related functional gastrointestinal disorders (fgids). objectives ...

background uremic pruritus is a common and bothersome complaint among end-stage renal disease which affect between 25% and 60% of this population .but there is no decisive cure for treatment of it. in this study, the effects of omega-3 for treatment of pruritus were investigated in hemodialysis patients. methods a double-blind randomized study was carried out in the form of placebo-controlled c...

Objective: Pharmacotherapy for premature ejaculation has been widely used years. The efficacy of antidepressants, especially SSRIs, confirmed by many randomized controlled studies. orthosympathetic activity on the ejaculatory system is a well-studied entity. In this study, our purpose to evaluate selective α-1 blocker, doxazosin, in treatment ejaculation. Material and Methods: study comprised 4...

The present study was conducted to explore the efficacy and safety of a herbal combination in the treatment of women with hyperlipidemic type 2 diabetes. The herbal combination capsule (600 mg) contained Terminalia chebula fruit extract (200 mg), Commiphora mukul (200 mg), and Commiphora myrrha oleo-gum-resin (200 mg), and the placebo capsule contained 600 mg toast powder. The patients in one g...

BACKGROUND Regarding to the growing prevalence of nonalcoholic fatty liver disease (NAFLD), concentrating on various strategies to its prevention and management seems necessary. The aim of this study was to determine the effects of symbiotic on C-reactive protein (CRP), liver enzymes, and ultrasound findings in patients with NAFLD. METHODS Eighty NAFLD patients were enrolled in this randomize...

Certain epidemiological and experimental studies suggest that n-3 fatty acids and folate can reduce blood pressure (BP). We investigated the effect of a daily supplementation with dietary doses of B-vitamins or n-3 fatty acids for 5 years on BP in patients with a history of CVD who participated in the Supplémentation en Folates et Omega-3 trial. The patients (n 2501; 1987 men and 514 women) wer...