objective: we conducted a double-blind, placebo-controlled study to determine the efficacy of an herbal sexual supplement (vigrx) on premature ejaculation (pe). method: a randomized double blind study was conducted on a fixed dose of herbal vigrx at roozbeh psychiatry hospital, tehran university of medical sciences. the sample consisted of 85 married patients diagnosed with primary pe according...

fatigue is recognized as one of the most disabling and frequent symptoms of multiple sclerosis (ms). amantadine appears to have some proven ability to alleviate the fatigue in ms. the aim of this study was to assess the efficacy of co-administration of amantadine and aspirin for the treatment of fatigue in multiple sclerosis. forty-five ambulatory patients aged 20–50 years with a diagnosis of m...

background: to compare the efficacy of metronidazole versus placebo in the control of gaseous symptoms inpatients with functional bowel disease. materials and methods: in the absence of organic or systemic diseases, all cases with chief complaints of bloating and normal laboratory tests were consecutively enrolled in this double-blind study. lactase deficiency and bacterial overgrowth were rule...

Background: We aimed to compare the efficacy of local injection therapies for lateral epicondylitis in a Bayesian framework. Methods: We searched the Embase, PubMed, Cochrane Central Register of Controlled Trials, Web of Science, Scopus, and ProQuest, for randomized controlled trials published from inception to February 2021 in any languages. The injection therapies included corticosteroids (C...

purpose: to evaluate the effect of oral tranexamic acid, oral prednisolone and placebo on prevention of recurrent hemorrhage in traumatic hyphema. methods: this randomized placebo-controlled double-blind clinical trial was performed on 182 subjects affected by hyphema after blunt trauma. the patients were hospitalized for at least 5 days and were randomly assigned for receiving oral tranexamic ...

Background and Aims: Laryngospasm and vomiting occurring after tracheal extubation in children is potentially dangerous. The aim of this study was to investigate the effects of preoperative 0.5 mg/kg i.v. Dexamethasone on the incidence of postextubation laryngospasm, and vomiting in children after tonsillectomy. Material and Methods : This study was performed at the Ilam Imam Khomeini hospital,...

A placebo is a treatment that is expected to have no inherent pharmacological or physical benefit — for instance, a starch capsule given for anxiety or pain, or sham surgery in which the critical surgical procedure is not performed. Placebos are often used for comparison in clinical studies, as a baseline against which to evaluate the efficacy of investigational clinical treatments. However, pl...

Background: Hydrogen-rich water (HRW) has been shown to have a stimulating effect on the human body. Objective: The aim of study was assess influence acute HRW intake autonomic cardiac regulation during 50 min rest sitting. Methods: Fourteen healthy females (age 21.7 ± 1.2 years, body mass 67.8 8.7 kg, height 167 5.5 cm) took part in this double-blind, randomized, placebo-controlled trial with ...

Background: There is a knowledge gap in systematic reviews on the impact of opioid agonist treatments mental health.Objectives: We compared health outcomes between different and placebo/waitlist, opioids themselves.Methods: This meta-analysis randomized clinical trials (RCTs) was pre-registered at PROSPERO (CRD42018109375). Embase, MEDLINE, PsychInfo, CINAHL Complete, Web Science Core Collectio...