Let G be a group acting properly and essentially on an irreducible, non-Euclidean finite dimensional CAT(0) cube complex X without a global fixed point at infinity. We show that for any finite collection of simultaneously inessential subgroups {H1, . . . , Hk} in G, there exists an element g of infinite order such that ∀i, 〈Hi, g〉 ∼= Hi ∗ 〈g〉. We apply this to show that any group, acting faithf...

Piwi-interacting RNAs (piRNAs) suppress transposon activity in animal germ cells. In the Drosophila ovary, primary Aubergine (Aub)-bound antisense piRNAs initiate the ping-pong cycle to produce secondary AGO3-bound sense piRNAs. This increases the number of secondary Aub-bound antisense piRNAs that can act to destroy transposon mRNAs. Here we show that Krimper (Krimp), a Tudor-domain protein, d...

To simplify the programming of hierarchical and distributed-memory parallel systems, the notion of shared virtual memory (SVM) has been proposed. This abstraction provides the programmer with the illusion of a at global address space and coherence is maintained at the page level. The success of this abstraction depends on the eeciency of page management. This in turn depends on the eeciency of ...