Background Heterogeneous nuclear ribonucleoprotein A2 (hnRNP-A2) belongs to a heterogenous family of nuclear proteins, importantly involved in mRNA traffi cking, translational and transcriptional processes. Recent evidence let suggest that hnRNPs post-transcriptionally modulate expression of infl ammatory mediators such as cyclooxygenase-2, tumour necrosis factor α (TNFα), interleukin 1β (IL-1β...

The development of two different immunoassays for the determination fumonisin B1 in wheat samples is reported. A previously described mimopeptide (FB1) was used to produce fusion proteins combination with luciferases: Gaussia luciferase (GLuc) and NanoLuc (NLuc). production, expression based on these (A2-GLuc A2-NLuc) detailed. assay showing best performance, A2-NLuc, a limit detection 0.61 ng ...

The purpose of this article is to introduce a new subclass analytic and bi-univalent functions, in associated with sigmoid function investigate the upper bounds for |a2| |a3|, where a2, a3 are initial Taylor-Maclaurin coefficients. Further we obtain Fekete-Szego inequalities class sigma. We also give several illustrative examples functionclass which here.

Let B(n) denote the collection of all set partitions of [n]. Suppose A1,A2 ⊆ B(n) are cross-intersecting i.e. for all A1 ∈ A1 and A2 ∈ A2, we have A1 ∩A2 6= ∅. It is proved that for sufficiently large n,

Pig phospholipase A2, pig iso-phospholipase A2 and bovine pancreatic phospholipase A2 were reacted in solution with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide, in the presence of N-hydroxysulfosuccinimide, at pH 7. The influence of micellar protectants was analyzed. In the presence of n-hexadecylphosphocholine, the losses of activity in micellar diheptanoyl-lecithin were 80, 35, and 10% in b...

and Applied Analysis 3 Step 1. Let F {a} be singleton. Then, there are u ∈ U and v ∈ V such that ‖uv‖ < M, and ‖ u, v, a − a‖ < M 1 . 2.2 Letting w uv ◦ uv, then ‖ uv ◦ uv, a − a‖ ‖ u, v, u, v, a − a − u, v, a − a ‖ < . 2.3 Step 2. Let F {a1, a2}. There is a u1, v1 ∈ U × V such that ‖ u1, v1, a1 − a1‖ < / 1 M , and for u1, v1, a2 − a2 ∈ A there is a u2, v2 ∈ U × V such that ‖ u2, v2, u1, v1, a2...

Cytokinesis requires the formation of an actomyosin contractile ring between the two sets of sister chromatids. Annexin A2 is a calcium- and phospholipid-binding protein implicated in cortical actin remodeling. We report that annexin A2 accumulates at the equatorial cortex at the onset of cytokinesis and depletion of annexin A2 results in cytokinetic failure, due to a defective cleavage furrow ...

BACKGROUND Visceral leishmaniasis (VL) is a severe vector-born disease of humans and dogs caused by Leishmania donovani complex parasites. Approximately 0.2 to 0.4 million new human VL cases occur annually worldwide. In the new world, these alarming numbers are primarily due to the impracticality of current control methods based on vector reduction and dog euthanasia. Thus, a prophylactic vacci...

Although overexpression of cyclin A2 is reportedly an indicator of a poor prognosis of various malignancies including endometrial carcinoma, its molecular mechanism remains undetermined. To address this issue, we examined the effect of cyclin A2 on the development of resistance to chemotherapeutic drugs. The expression of cyclin A2 protein was increased in advanced-stage and chemotherapy-refrac...

Aims: To assess the accuracy and precision of measuring haemoglobin A2 by high performance liquid chromatography (HPLC) in the presence and absence of sickle cell trait, with or without a thalassaemia trait. Methods: The haemoglobin A2 percentage and the haemoglobin A2 plus S percentages were determined by HPLC on 82 normal controls and 78 patients with sickle cell trait, respectively; the a th...