Acquired prosopagnosia is characterized by a deficit in face recognition due to diverse brain lesions, but interestingly most prosopagnosic patients suffering from posterior lesions use the mouth instead of the eyes for face identification. Whether this bias is present for the recognition of facial expressions of emotion has not yet been addressed. We tested PS, a pure case of acquired prosopag...

Microbial antagonism in an Arctic soil habitat was demonstrated by assessing the inhibitory interactions between bacterial isolates from the same location. Of 139 isolates obtained from five soil samples, 20 antagonists belonging to the genera, Arthrobacter, Pseudomonas and Flavobacterium were identified. Inter-genus, inter-species and inter-strain antagonism was observed between the interactin...

Phosphatidylserine decarboxylase catalyzes the last step in the pathway leading to phosphatidylethanolamine, the principal membrane lipid of E. coli. Mutants of E. coli have now been isolated in which this enzyme is theramolabile. The structural gene for phosphatidylserine decarboxylase (psd gene) is closely linked to the pur A locus at about 83 min on the standard map of the E. coli chromosome...

Multiple tumor-derived factors are responsible for the accumulation and expansion of immune-suppressing myeloid-derived suppressor cells (MDSC) and M2-like tumor-associated macrophages (TAM) in tumors. Here, we show that treatment of tumor-bearing mice with docetaxel in combination with the phosphatidylserine-targeting antibody 2aG4 potently suppressed the growth and progression of prostate tum...

The nitrosourea alkylating agent, carmustine, is used as chemotherapeutic drug in several malignancies. The substance triggers tumor cell apoptosis. Side effects of carmustine include myelotoxicity with anemia. At least in theory, anemia could partly be due to stimulation of eryptosis, the suicidal death of erythrocytes, characterized by cell shrinkage and breakdown of phosphatidylserine asymme...

Cholesterylphosphoryldimethylethanolamine is a zwitterionic compound which is a good bilayer stabilizer. As has been found with many other compounds having these properties, cholesterylphosphoryldimethylethanolamine is found to be a potent inhibitor of protein kinase C in both vesicle and micelle assay systems. The kinetics of the inhibition in Triton X-100 micelles was non-competitive with res...

Background and Aims : Circulating microvesicles (MVs) are membrane-enclosed particles shed from activated cells. The NLRP3-inflammasome the interleukin 6 (IL-6)-pathways essential in cardiovascular disease. Knowledge of how inflammasome-related inflammation impacts secretion MVs is limited. We aimed to investigate whether plasma associate with genes encoding inflammasome-signaling coronary thro...

Received June 24, 2008. Accepted January 28, 2009. Corresponding author: Azize Sener, Department of Biochemistry, Faculty of Pharmacy, Marmara University, Tibbiye Cad., No: 49, 34668, Haydarpasa-Istanbul, Turkey. Phone: +90 216 414 29 62; e-mail: [email protected] Abbreviations: apoB100 – apolipoprotein B100, apoER2 – apolipoprotein E receptor 2, FITC – fluorescein isothiocyanate, GpIIb/ I...