BACKGROUND The common variants in the fat mass and obesity-associated (FTO) gene have been associated with obesity and insulin resistance. Recently, studies also linked FTO variants with macronutrient intakes. OBJECTIVE We aimed to investigate whether diet interventions varying in macronutrients modified the effects of FTO genotypes on changes in insulin resistance. METHODS We genotyped FTO...

A spline animal model was fitted to 152,103 test-day milk, fat, and protein yield records from 14,423 first-lactation cows. The models included age at calving and the herd-test-month as fixed effects. Model fitting was carried out using Restricted Maximum Likelihood with ASREML. For milk yield, the heritability at 18 d in milk was 0.19, which increased to the maximum estimated value of 0.23 at ...

background: overweight and obesity increasing world wide because of changing life style and dietary habits. diet therapy plays an important role to prevent obesity outcomes. the aim of this study was determining the effects of diet therapy on weight reduction and fitness. methods: a clinical trial study was conducted using convenient sampling method and 216 subjects (190 female and 26 male) wer...

Background Individuals with early or intermediate stages of age-related macular degeneration (AMD) make up a large, growing segment of the elderly population. Evidence is sparse regarding modifiable factors that may decrease the risk of progression to the advanced forms of AMD. Objective To advise patients with a high risk for advanced forms of AMD about preventive measures through our evaluati...

BACKGROUND Low intake of fat and high intake of specific vitamins have been hypothesized to reduce risk of basal cell carcinoma of the skin (BCC). OBJECTIVE Our objective was to examine intakes of fat, antioxidant nutrients, retinol, folate, and vitamin D in relation to risk of BCC. DESIGN In 1986, diet was assessed by a validated food-frequency questionnaire in 43217 male participants of t...

A survey on opium use was earned out in Tinsukia district of upper Assam to assess the present prevalence and pattern of opium abuse and compared with earlier findings of the year 1981 (Baruah et al., 1995). A total of 75 addicts could be detected during the survey and 61 were interviewed using structured questionnaire. The results indicate significant decline in prevalence in opium use over th...

The pattern of fat distribution is related to a large number of variables of clinical importance. Many anthropometric indices have been derived which are surrogate measures of central fat distribution. However, systematic information on age variations in regional adiposity and central fat distribution is incomplete. The present study investigates the age variations in regional adiposity and fiv...

BACKGROUND Breastfeeding may lower chronic disease risk by long-term effects on hormonal status and adiposity, but the relations remain uncertain. OBJECTIVE To prospectively investigate the association of breastfeeding with the growth hormone- (GH) insulin-like growth factor- (IGF) axis, insulin sensitivity, body composition and body fat distribution in younger adulthood (18-37 years). DESI...

saturated fat consumption increases the risk of both coronary and cancer diseases. therefore, fat reduction in uf-feta cheese (≈ 45% fdm) is favorable but, unfortunately, it has some negative effects on the texture and sensory characteristics of the cheese. in this research, response surface methodology was employed to study the probably improving effects of wpc80 (0-20 gr kg-1), lecithin (0-2 ...

BACKGROUND Previous research relating dietary fat, a modifiable risk factor, to pancreatic cancer has been inconclusive. METHODS We prospectively analyzed the association between intakes of fat, fat subtypes, and fat food sources and exocrine pancreatic cancer in the National Institutes of Health-AARP Diet and Health Study, a US cohort of 308 736 men and 216 737 women who completed a 124-item...