Background: The adaptor protein Src homology 3 domain-binding 2 (SH3BP2) is widely expressed in immune cells. It controls intracellular signaling pathways. present study was undertaken to investigate the role of SH3BP2 a murine systemic lupus erythematosus model. Methods: For model, we used Faslpr/lpr mice. Clinical and immunological phenotypes were compared between SH3BP2-deficient Splenomegal...

I shall briefly survey the current status on more rigorous studies of chaos in fluids by focusing along the line of chaos phenotypes: sensitive dependence on initial data, and recurrence.

I N a search for polymorphisms in plasma proteins of turkeys, we observed differences in the electrophoretic patterns of proteins which migrated in the region of the alb~rnins.~ On tracing the pedigrees of the birds it became apparent that the alleles for the three albumin types were segregating only in descendants from a cross between the domestic species (Meleagris gallopavo) and the ocellate...

Chronic obstructive pulmonary disease (COPD) is now considered a markedly complex and heterogeneous disease [1]. In the latest update of the Global Initiative for Chronic Obstructive Lung Disease (GOLD 2017) [2], the definition of COPD has been revised to emphasise the heterogeneity of this disease. The phrase “airway and/or alveolar abnormalities” replaces “an enhanced chronic inflammation” in...

In simple terms, a phenotype is a collection of characteristics that arise through the expression of the genes of an organism, in an environment. Some examples of phenotypes are the red eyes of a typical fruitfly, Drosophila melanogaster; the length of a body part such as the tail of a mouse; high blood pressure in the arteries of a human, sensitivity to a chemical or to light; reduced mass of ...

There can no longer be any doubt that, within the spectrum On this dubious basis, a third phenotype with a peak prevalence at six years was identified between the group of of wheezing disorders of childhood, several distinct phenoearly transient wheezers and later atopic asthmatic subjects. types can be recognised. Although clinicians have been The distinction between children who wheezed in th...

Moroccan goats are characterized by the presence of different populations identified only based on their phenotypes. The objectives of this study were to assess the genetic differentiation of the Draa goat breed and to analyze its genetic structure and its relationships with other local populations using 12 microsatellite markers. The screening was done in South Eastern and Southern Morocco on ...