Abstract Mesenchymal stem cells (MSCs) have great potential for application in cell therapy and tissue engineering procedures because of their plasticity capacity to differentiate into different types. Given the widespread use MSCs, it is necessary better understand some properties related osteogenic differentiation, particularly those linked biomaterials used engineering. The aim this study wa...

The synergistic effects of extracellular matrix (ECM) proteins combination on Hep3B cell proliferation and functions are studied herein. Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) microspheres were covalently conjugated with three types of proteins, collagen (type I), laminin and fibronectin by using 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide and Nhydroxysuccinimide cross linkers. ...