نتایج جستجو برای: ph sensitive

تعداد نتایج: 439223  

Journal: :Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2015
Yoshihiro Tokudome Kaoru Nakamura Yurina Itaya Fumie Hashimoto

PURPOSE Enhance skin penetration of hydrophilic and lipophilic compounds using liposomes that are responsible to the pH of the skin surface. METHODS pH-sensitive liposomes were prepared by a thin layer and freeze-thaw method with dioleoyl phosphatidyl ethanolamine and cholesteryl hemisuccinate. Liposomal fusion with stratum corneum lipid liposomes was measured using fluorescence resonance ene...

A micro-fabricated metal-oxide based conductometric pH sensor is designed and fabricated in this manuscript. pH sensors have applications in various areas from farming to food processing, human health monitoring, industrial waste products investigation, etc. Accordingly, there is a relatively high demand for a reliable, rapid and precise pH sensor in the market. Relatively precise pH sensors ha...

2015
Muhammad Naeem Jiafu Cao Moonjeong Choi Woo Seong Kim Hyung Ryong Moon Bok Luel Lee Min-Soo Kim Yunjin Jung Jin-Wook Yoo

Current colon-targeted drug-delivery approaches for colitis therapy often utilize single pH-triggered systems, which are less reliable due to the variation of gut pH in individuals and in disease conditions. Herein, we prepared budesonide-loaded dual-sensitive nanoparticles using enzyme-sensitive azo-polyurethane and pH-sensitive methacrylate copolymer for the treatment of colitis. The therapeu...

Journal: :The Journal of antimicrobial chemotherapy 2006
Tahseen H Nasti Masood A Khan M Owais

OBJECTIVES To evaluate the efficacy of pH-sensitive liposomes of nystatin against Cryptococcus neoformans infection in a murine model. METHODS In the present study, we investigated the antifungal activity of nystatin entrapped in pH-sensitive liposomes in a murine model. Mice infected with C. neoformans were treated with nystatin in neutral egg phosphatidylcholine (egg-PC) liposomes, as well ...

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