Dielectric stack interference ® lters can be used in conjunction with a high-throughput single-stage spectrograph to facilitate the measurement of high signal-to-noise (S/N) ultraviolet (UV) Raman spectra with 228.9-nm and 244-nm excitation wavelengths. Placed between the sample and the spectrograph, these ® lters re ̄ ect Rayleigh scattering while transmitting Stokes-shifted Raman scattering. W...

RATIONALE The nitrated sugar alcohols mannitol hexanitrate (MHN), sorbitol hexanitrate (SHN) and xylitol pentanitrate (XPN) are in the same class of compounds as the powerful military-grade explosive pentaerythritol tetranitrate (PETN) and the homemade explosive erythritol tetranitrate (ETN) but, unlike for PETN and ETN, ways to detect MHN, SHN and XPN by mass spectrometry (MS) have not been fu...

Organic nitrates, such as nitroglycerin (GTN), isosorbide-5-mononitrate and isosorbide dinitrate, and pentaerithrityl tetranitrate (PETN), when given acutely, have potent vasodilator effects improving symptoms in patients with acute and chronic congestive heart failure, stable coronary artery disease, acute coronary syndromes, or arterial hypertension. The mechanisms underlying vasodilation inc...