Standard MR imaging and CT are routinely used for anatomic diagnosis in brain tumors. Pretherapy planning and posttreatment response assessments rely heavily on gadolinium-enhanced MR imaging. Advanced MR imaging techniques and PET imaging offer physiologic, metabolic, or functional information about tumor biology that goes beyond the diagnostic yield of standard anatomic imaging. With the adve...

The purpose of this study was to evaluate the accuracy of Glu-NH-CO-NH-Lys-(Ahx)-[68Ga(HBED-CC)] PET compared with morphologic imaging for the assessment of lymph node metastases (LNM) in patients with recurrent prostate cancer. METHODS Forty-eight patients (median age, 71 y; interquartile range, 66-74 y) with biochemical recurrence (median prostate-specific antigen level, 1.31 ng/mL; interqu...

UNLABELLED Recent reports have indicated the value and limitations of (18)F-FDG PET and (201)Tl SPECT for determination of malignancy. We prospectively assessed and compared the usefulness of these scintigraphic examinations as well as (18)F-FDG PET delayed imaging for the evaluation of thoracic abnormalities. METHODS Eighty patients with thoracic nodular lesions seen on chest CT images were ...

objective(s): the aim of this study was to analyze detection rates and effectiveness of 18f-fluorodeoxyglucose positron emission tomography (fdg-pet) cancer screening program for prostate cancer in japan, which is defined as a cancer-screening program for subjects without known cancer. it contains fdg-pet aimed at detection of cancer at an early stage with or without additional screening tests ...

Introduction:Myocardial 18F-FDG uptake is highly variable in oncologic whole body 18F-FDG PET/CT studies, ranging from quite intense to minimal distribution. Intense or heterogeneous myocardial 18F-FDG uptake is undesirable as it may interfere with the visual or quantitative evaluation of tumoral invasion and metastases in pericardium, myocardiu...

Introduction: Orbital metastasis of prostate cancer (PC) is very rare and even more unique in castration-resistant PC (CRPC). In this scenario, choline positron emission tomography/computed tomography (choline PET/CT) is the gold-standard restaging method of choice available in our setting, and new anti-androgens treatments show improvement in overall survival. Case presentation: We report the...

The diagnosis of prosthetic valve endocarditis continues to present a diagnostic challenge, due to the lower sensitivity of the modified Duke criteria and a higher percentage of negative or inconclusive echocardiography results. Diagnostic delay might result in significant morbidity/mortality. Imaging modalities like 2-[18F]fluoro-2-deoxy-D-glucose positron emission tomography/comput...

Simultaneous positron emission tomography and magnetic resonance imaging (PET-MR) is an innovative and promising imaging modality that is generating substantial interest in the medical imaging community, while offering many challenges and opportunities. In this study, we investigated whether MR surface coils need to be accounted for in PET attenuation correction. Furthermore, we integrated moti...

Purpose Although recent data from the literature suggest that PET imaging with [18]-Fluorodeoxyglucose (18F-FDG) is a promising technique in multiple myeloma (MM), the development of other radiopharmaceuticals seems relevant. CD138 is currently used as a standard marker in many laboratories for the identification and purification of myeloma cells, and could be used in phenotype tumor imaging. I...

Molecular imaging with positron-emitting radionuclides is playing an increasingly important role in the diagnosis and staging of malignant disease and in monitoring response to therapy. To meet this challenge, significant improvements in the performance of the imaging technology have been achieved in recent years. Such developments are subject to the constraints imposed by the physics of positr...