Pesticide risk assessments are usually based on short-term acute toxicity tests, while longer-term population dynamic related traits, critical to the success of biological control and Integrated Pest Management (IPM) programs, are often overlooked. This is increasingly important with respect to new biopesticides that frequently cause no short-term acute effects, but that can induce multiple phy...

Prior to October 2007, the US Environmental Protection Agency (EPA) required both 13-week and 1-year studies in Beagle dogs be submitted in support of registration for pesticides. Following an extensive retrospective analysis, we (the authors) determined that the 1-year toxicity dog study should be eliminated as a requirement for pesticide registration. The present work presents this retrospect...

EPA’s Office of Pesticide Programs (OPP) is committed to improving and transforming its approaches to pesticide human health and ecological risk assessment and management by increasing the efficiency and effectiveness of testing for risk assessment to inform decisions and to reduce the cost of the process both in dollars and animals. OPP is building on the ambitious NAS vision for Toxicity Test...

diazinon is commonly used for pest control in the agricultural fields surrounding freshwater reservoirs. this study was conducted to determine the chronic toxicity of organophosphorous pesticide and its effects on some hematological parameters and biochemical blood plasma profiles of common carp, cyprinus carpio. diazinon was applied at concentrations of 60 and 120î¼g/l preparations in 10, 20 a...

The agricultural industry and urban pesticide users are increasingly relying upon pyrethroid insecticides and shifting to more potent members of the class, yet little information is available on residues of these substances in aquatic systems under conditions of actual use. Seventy sediment samples were collected over a 10-county area in the agriculture-dominated Central Valley of California, w...