BACKGROUND The aim of the publication is to show differences among patients with the first detected episode of atrial fibrillation (AF), paroxysmal, and persistent AF patients, for whom cardioversion was planned in the hospital setting in Poland. METHODS We present an analysis of the Polish cohort of the multicenter, multinational RHYTHM-AF registry. Consecutive patients in the hospital setti...

This work introduces a number of algebraic topology approaches, including multi-component persistent homology, multi-level persistent homology, and electrostatic persistence for the representation, characterization, and description of small molecules and biomolecular complexes. In contrast to the conventional persistent homology, multi-component persistent homology retains critical chemical and...

The motor cortex generates synchronous network oscillations at frequencies between 7 and 14 Hz during disinhibition or low [Mg]o buffers, but the underlying mechanisms are poorly understood. These oscillations, termed here ∼10 Hz oscillations, are generated by a purely excitatory network of interconnected pyramidal cells because they are robust in the absence of GABAergic transmission. It is li...

It has been reported that long-term enhancement of superficial dorsal horn (DHs) excitatory synaptic transmission underlies central sensitization, secondary hyperalgesia, and persistent pain. We tested whether impaired clearance of K(+) and glutamate by glia in DHs may contribute to initiation and maintenance of the CNS pain circuit and sensorimotor abnormalities. Transient exposure of the spin...

Intracellular recordings from spontaneously spindling GABAergic neurons of the ferret perigeniculate nucleus in vitro revealed a fast afterhyperpolarization after each action potential, a medium-duration afterhyperpolarization after each low-threshold Ca2+ spike, and a slow afterhyperpolarization after the cessation of spindle waves. The slow afterhyperpolarization was associated with an increa...

In the covalently linked 2D coordination network {[Fe(bbtr)(3)](BF(4))(2)}(∞), bbtr = 1,4-di(1,2,3-triazol-1-yl)butane, the iron(II) centers stay in the high-spin (HS) state down to 10 K. They can, however, be quantitatively converted to the low-spin (LS) state by irradiating into the near-IR spin allowed (5)dd band and back again by irradiating into the visible (1)dd band. The compound shows t...

We describe an efficient parallel algorithm for hiddensurface removal for terrain maps. The algorithm runs in O(log n) steps on the CREW PRAM model with a work bound of O((n + k)polylog(n)) where n and k are the input and output sizes respectively. In order to achieve the work bound we use a number of techniques, among which our use of persistent data-structures is somewhat novel in the context...

Using T50 Monte Carlo simulation, we study the relaxation of graph coloring ~K-COL! and satisfiability ~K-SAT!, two hard problems that have recently been shown to possess a phase transition in solvability as a parameter is varied. A change from exponentially fast to power law relaxation, and a transition to freezing behavior are found. These changes take place for smaller values of the paramete...

A point location scheme is presented for an n-veriet dynamic planar subdivision whose underlying graph is only required to be connected. The scheme uses O(n) space, yields an O(log2 n) query time and an O(1ogn) update time. Insertion (resp. deleiion) of an arbitrary k-edge chain inside a region can be performed in O(klog(n+k)) (resp. O(k1ogn)) iime. The scheme is then ectended to speed up the i...