BACKGROUND Most of the current anti-fungal treatments are chemical-based, fungistatic, have low efficacy in the treatment of tinea and toxicity concerns, while onychomycosis remains recalcitrant to most antifungal therapies. The study aimed to establish the fungicidal, efficacy and safety profile of Calmagen® dermaceutical cream and lotion containing AMYCOT® as a topical treatment in patients w...

The expression of some insect P450 genes can be induced by both exogenous and endogenous compounds and there is evidence to suggest that multiple constitutively overexpressed P450 genes are co-responsible for the development of resistance to permethrin in resistant mosquitoes. This study characterized the permethrin induction profiles of P450 genes known to be constitutively overexpressed in re...

Radiocarbon from I4C-acidand 14C-alcohol-labeled preparations of transand cis-permethrin administered orally to lactating Jersey cows for three consecutive days at 1.0 mg/kg is largely eliminated from the body within 12 or 13 days after the initial treatment. Milk and fat residues, although relatively low, are higher with cisthan with trans-permethrin and consist almost entirely of unmetabolize...

Objectives To assess the effectiveness of nanopermethrin as a potential new formulation for pest and vector control. Methods Permethrin nanoparticles were prepared by ionic gelation method its structure formulations designed using Box–Behnken statistical technique. The effect independent variables (Chitosan/Permethrin ratio, tripolyphosphate quantity, sonication time) on properties was investig...

BACKGROUND Sun protection materials have been one of the major concerns in pharmaceutical in-dustry since almost one century ago. Various materials have been found to have such an effect but there are still many unknown substances that have not been discovered. Objective : To introduce a novel mineral-based sun lotion with considerable UV absorption properties compared to commercially available...

In this study, Tithonia diversifolia Helms. (A Gray), Aloe secundiflora (Miller) and Azadirachta indica (A. Juss) plant extracts were used to make herbal soaps while Thevetia peruviana (Schum) seed oil was used to make a herbal lotion for skincare. The soaps were tested for the growth inhibition of Escherichia coli, and Candida albicans. The lotion was evaluated against Staphylococcus aureus an...

Introduced parasites are a threat to biodiversity when naïve hosts lack effective defenses against such parasites [1]. Several parasites have recently colonized the Galápagos Islands, threatening native bird populations [2]. For example, the introduced parasitic nest fly Philornis downsi (Diptera: Muscidae) has been implicated in the decline of endangered species of Darwin's finches, such as th...

In October, FDA approved a prescription (Rx)-to-OTC conversion for the head lice removal product ivermectin (Sklice) 0.5% lotion. Health care experts and others hope OTC availability of will improve patients' accessibility to treatment. “I agree with change from OTC, as it [will] increase access this medication—no doctor visit needed or delay in treatment due lack available timely appointments ...

Objective: The purpose of this study was to formulate a phytosome lotion from Mangkokan leaf using green solvent extraction. Methods: Ionic liquid, 1-butyl-3-methylimidazolium tetrafluoroborate, combined with microwave-assisted extraction, used obtain flavonoid compounds. extract formulated into three different ratios phospholipon (1:0.5), (1:1), and (1:2). Three formulas were analyzed identify...

background: sun protection materials have been one of the major concerns in pharmaceutical industry since almost one century ago. various materials have been found to have such an effect but there are still many unknown substances that have not been discovered. objective: to introduce a novel mineral-based sun lotion with considerable uv absorption properties compared to commercially available ...