Periventricular leukomalacia is a disorder of white matter injury that is frequently found in premature infants and is the major cause of cerebral palsy. However, only a few cases of periventricular leukomalacia have been reported prenatally. Ultrasound investigation of the periventricular region could provide clues for the prenatal diagnosis and prediction of cerebral palsy. Herein, we report ...

Two hundred infants of below 1501 g at birth were regularly examined with real time ultrasound using a 7.5 MHz transducer. Abnormalities were categorized as periventricular haemorrhage (PVH) (n = 107) or periventricular leucomalacia (PVL), with or without PVH (n = 52). Of the group with PVL, 25 had the appearances of prolonged flare without cavitation. Prospective assessments of up to 50 potent...

A 34-year-old epilepsy woman had first seizure when aged 14. Seizure patterns are mainly simple partial type, presented by a sense of air within chest wall rising to head or focal twitching of right hand. She also had generalized tonicclonic seizures before. In recent four years, she did not experience generalized seizure although simple partial seizures were noted average four to five times a ...

The later neurodevelopmental progress of 15 babies who had neonatal periventricular echodensities or flares in the absence of any intraventricular bleeding or subsequent cystic degeneration was studied. At follow up four infants had neurological abnormalities, including spastic diplegia (n = 2). These findings suggest that transient flares may represent mild periventricular leucomalacia with co...

Glioblastomas in adults are highly heterogeneous tumors that can develop throughout the brain. To date no predictive-location marker has been identified. We previously derived two glioblastoma cell lines from cortical and periventricular locations and demonstrated distinct transcriptomic profiles. Based on these preliminary results, the aim of this study was to correlate glioblastoma locations ...

The results of serial MR imaging of the brain in 32 patients with neonatal cerebral injury who had two or more examinations are reviewed. By comparison with normal age-matched controls, delayed or deficient myelination was identified in eight patients on follow-up examination. Developmental delay was present in all of these patients. In three patients delayed myelination was identified at the f...

Cerebral palsy (CP) It is a diagnostic term used to describe a group of motor syndromes. a static encephalopathy, a term previously used, is now inaccurate because of the recognition that the neurologic features of CP often change or progress over time. Although CP is often associated with epilepsy and abnormalities of speech, vision, and intellect, it is the selective defect of the brain's mot...

OBJECTIVE To present a critical and up-to-date review of ischemic brain damage in premature, very low birth weight infants. SOURCES OF DATA Articles were obtained by means of a search of the MEDLINE database, with those considered most representative by the authors being selected. SUMMARY OF THE FINDINGS The most frequent ischemic injuries among preterm, very low birth weight neonates are h...