The role of obturation in root canal treatment, although considered secondary to debridement and disinfection, still remains a critical stage for a successful outcome. The aim of obturation is to seal the periradicular tissues from the residual microorganisms left in the root canal system after chemomechanical debridement. Obturation of the root canal space has been performed using various tech...

This case report describes the endodontic treatment of a large cyst-like periradicular lesion using a combination of antibiotic drugs. A 15-yr-old boy with a large cyst-like lesion from the apices of his teeth 29 to 31. Conservative root canal treatment was performed (tooth #30). During treatment procedure, 2.5% sodium hypochlorite solution was used for irrigation and a combination of antibioti...

Prostaglandins (PG) have been implicated in the genesis of periapical lesions. Periapical specimens from patients with clinical signs and symptoms of chronic and acute apical periodontitis were obtained and immediately frozen in liquid nitrogen. Periradicular tissues from unerupted third molars were frozen and used as controls. The concentration of PGE2 was determined by radioimmunoassay. Low l...

Four clinical cases of immature teeth that developed periradicular periodontitis or abscess underwent a conservative treatment approach, i.e. without canal instrumentation. Instead, only copious 2.5% NaOCl irrigation was performed. All cases presented herein developed mature apices after 7 months to 5 years after the initial treatment without complications, although narrowing canal space was ob...

Apical periodontitis is an inflammatory disorder of periradicular tissues caused by aetiological agents of endodontic origin. The subject has been reviewed by Nair. (1)(2) They are believed to result from inflammatory processes in the periapical tissues associated with bacterial infection and necrosis of the dental pulp in carious teeth. As a consequence of these processes and the inability of ...

Antibiotics are a valuable addition to health practitioners for the management of bacterial infections. During endodontic treatment and when managing trauma to the teeth, antibiotics may be applied systemically or locally. Due to the potential risk of adverse effects of systemic applications, and the ineffectiveness of systemic prescribed antibiotics in necrotic or pulpless teeth and the perira...

Background: Pulp necrosis is a common detrimental consequence of dental traumatic injuries. Early management of such cases is mandatory in order to prevent subsequent pathological changes that could further complicate the treatment. Pulp necrosis, chronic and cystic apical periodontitis can be the fate if these teeth are left untreated. Despite these serious complications, root canal treatment ...

BACKGROUND Though success rates of endodontic initial treatment have been improving over the years, persistence of periapical disease is far from being a rare condition. The most common therapeutical options for the re-treatment of teeth with periapical pathosis are non-surgical orthograde treatment and surgical treatment. Selection between alternative treatments should be based on assessment o...