Abstract Tuberous sclerosis complex (TSC) is a multisystem disorder caused by loss-of-function mutations in TSC1/2 proteins. This results constitutive mTOR activation and predisposes to the development of benign tumours, with renal angiomyolipomas (AMLs) tuber-related drug-resistant epilepsy (DRE) being major causes morbidity mortality adults. Despite central role leukocyte biology beneficial i...

background and aim: in most infections and diseases, to cure and decrease the effect of disease, induction and increasing power of immuno system are necessary. nigella sativa is a plant that has been used for treatment of many diseases. in this survey, the effect of nigella sativa is surveyed in strengthening of monocyte phagocytosis so that the use and mechanism of this plant for strengthening...

the cytotoxic activity of natural killer cells is usually tested by radioactive assay csi cr release assay), which detects the release of cytoplasmic contents after plasma membrane disintegration of dying cells. in contrast to this indirect evaluation of cytotoxicity, the assessment of cell damage by flow cytometry aims to provide a more exact characterization of the death pathway via detection...

OBJECTIVE It has been found that asphyxia influences proliferation and differentiation of brain neural stem cells in newborn animal models, and that peripheral blood stem cells play an important role in repairing brain damage. But it has not been reported yet whether asphyxia influences peripheral blood stem cells differentiating into neural cells, and whether with the progress of the disease t...