Chronic perinatal hypoxia causes a significant loss of total brain volume, brain weight and cortical neuron number. These measures are completely reversed following recovery in normoxic conditions. Yet, the cellular and molecular mechanisms underlying this plasticity are not well understood. Here, we show that hypoxia from postnatal days 3 (P3) to 10-11 causes a 30% decrease in cortical neurons...

as fetal compensation against hypoxemia progresses, the afterload on the heart and peripheral vascular resistance increases. eventually, the right heart fails, which is transmitted to the fetal venous system, causing decreased flow during late diastole or atrial contraction and increased resistance in the ductus venosus and inferior vena cava. the ductus has forward flow during atrial contracti...

BACKGROUND Much of the data on still births and early neonatal deaths from resource-limited settings are obtained via maternal recall from national or community level surveys. While this approach results in useful information to be obtained, often such data suffer from significant recall bias and misclassification. In order to determine the prevalence of stillbirths (SB), early hospital neonata...

The aim – to evaluate the effectiveness of preventive ligation uterine vessels during caesarean section in women with placenta previa.
 Material and Methods. study was conducted on basis Regional Perinatal Center Maternity Hospital № 5 (Odessa) for 2000–2020 performing main stage cesarean after reducing perfusion placenta. Uterine performed fetal removal. volume blood loss, condition mothe...

There exists a paucity of data for socially disadvantaged populations describing patterns and predictors of asthma control status and exacerbations during pregnancy, and their relationship to adverse perinatal outcomes. Asthmatic women (n=189) were followed prospectively during pregnancy, with visits at 12, 20, 28 and 36 weeks gestation. Data on loss of control, recurrent uncontrolled asthma an...

OBJECTIVE To evaluate the maternal and perinatal outcomes of Alberta's regionalized system of care. In particular, to compare the outcomes of communities with limited or no local intrapartum care with those of regional and tertiary care centres. METHODS We conducted a population-based retrospective study of all Alberta deliveries in 1999 and 2000. Maternal outcome measures were rates of patie...

The success of pregnancy and infant loss support groups in helping parents, especially mothers, deal with the emotional trauma of stillbirth is well established in sociological and psychological research literature. More recent studies have focused on the emergence of virtual perinatal loss support groups and communities which offer a convenient means of accessing an extensive group of supporte...