The purpose of this note is to posit and discuss the concept of "competitive inhibition potential" (CIP), which is an in vivo index of the ability of a competitive inhibitor to elevate plasma concentrations of drug substrates, when the competitive inhibitor is administered at its usual and customary dose.

Objective: To evaluate lipoxygenase inhibitory, antioxidant, and antimicrobial activities of selected essential oils. Materials and Methods: Essential oils were obtained by hydro distillation using a Clevenger-type apparatus and oils composition was analyzed by gas chromatography-mass spectrometry. Lipoxygenase inhibitory activity of essential oils was evaluated by lipoxygenase inhibition assay...

Citrus hystrix DC. is a common herb in tropical regions. Its essential oils are now widely researched and applied because of their high economic value safety for humans interesting materials future trends. This review provides an extensive overview the biological activities C. oil, characterized predominantly by citronellal, ?-Pinene, sabinene, limonene, terpinene-4-ol, which deciding factors a...

Quantitative scaling into percent signal change is helpful to detect and eliminate “bad” results with abnormal extreme values. While cognitive effects give signal changes on the order of 1% (and larger in the visual and auditory cortices), signal variations of over 10% may arise from motion and other artifacts in the data. Thus, a quantitative check on measured effect size can be used to screen...

Mosquito attractants and spatial repellents hold great promise in controlling mosquito pests. In assessing the effectiveness of mosquito attractants and repellents, a good olfactometer system, and optimized testing conditions, are essential. In this research, we demonstrated the usefulness of an olfactometer system, and optimized testing conditions for Aedes albopictus (Diptera: Culicidae). We ...