OBJECTIVE To determine and compare antimicrobial susceptibility patterns of pathogenic bacteria from inpatients and outpatients at a university teaching hospital in Yaounde, Cameroon. METHODS Gram-negative bacilli isolates (n = 522), obtained from a wide range of clinical specimens (urine, pus and blood) from inpatients and outpatients at Yaounde Central Hospital between March 1995 and April ...

Probably most penicillinase-producing strains of Neisseria gonorrhoeae (PPNG) isolated in the Netherlands are sent to the Laboratory for Chemotherapy of the Rijks Instituut voor de Volksgezondheid (RIV). The co-operation between the RIV and the Office of the Chief Medical Officer of Health (CMOH) has resulted in a quarterly review of the PPNG strains isolated by the RIV Laboratory for Chemother...

Thirty-six strains of penicillinase-producing Neisseria gonorrhoeae (PPNG) were detected among 794 prostitutes between October 1981 and May 1982 in Surabaya, Indonesia. The high prevalence of PPNG strains among the high-class prostitutes and a lower prevalence among the low-class suggest that regular mass treatment for syphilis did not play an important role in the emergence and spread of PPNG;...

Since March 1976, 7 cases of PPNG have been identified in Alaska. However, 3 of these cases occurred in 1980. We recommend that all physicians and other health care providers be alert for any patient diagnosed as having gonorrhea who gives a history of exposure in Southeast Asia or the Philippines. Such patients should be cultured, the lab slip marked "test for possible PPNG", and treatment giv...

Ninety-seven patients with infections due to penicillinase-producing Neisseria gonorrhoeae (PPNG) were treated with single doses of gentamicin 280 mg intramuscularly. The failure rate among those followed up was 3%. No significant side effects were recorded. Gentamicin is a valuable alternative in the treatment of infections due to PPNG strains.

The title of this lecture is intentionally provocative. It is well known that there are many varieties of the enzyme that can split the /3-lactam bond of penicillins and/or cephalosporins (Fig. 1)-the specific reaction referred to generally as "peni-cillinase." And their physiological role in the life history of the bacteria which produce them is still a matter of controversy. But the case I wi...

Background: Once identified as Staphylococcus aureus, it is imperative to understand their methicillin resistance status for institution of appropriate therapy. Conventional disc diffusion tests may not accurately identify MRSA strains and may not be in concordance with PCR results. Objectives: Relative abilities of phenotypic and molecular methods to detect MRSA strains was evaluated to unders...

The number of infections with penicillinase-producing Neisseria gonorrhoeae (PPNG) strains in Singapore has risen from three in 1976 to 1792 in 1979. In the latter year they formed 19.2% of all infections with gonorrhoea, and 1280 of the strains isolated were from female prostitutes. The prevalence of PPNG infections is analysed according to the different sections of the community and racial gr...

aureus was isolated from two patients in the same ward of the Seattle Veterans Administration Hospital. This strain, called the Seattle variant, caused a fatal pneumonia in one of the patients and has been the object of a detailed laboratory investigation (R. J. Bulger, Ann. Internal Med., 67:81, 1967). The results indicate that the mechanism of resistance to methicillin was probably a combinat...