OBJECTIVE To report a case of Jarisch-Herxheimer reaction (JHR) in a patient with presumed neurosyphilis and HIV. CASE SUMMARY A 45-year-old HIV-positive man (CD4+ count 450 cells/mm(3) and history of AIDS-defining illness) presented with JHR after an initial intravenous dose of penicillin G for presumed neurosyphilis. The patient described feeling cold with worsening headache and chills appr...

Copyright © 2015 The Korean Association of Internal Medicine This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/ by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. pISSN 1226-3303 eISSN 2005-664...

The originally penicillin-induced, wall-less stable L-forms of Proteus vulgaris P18, isolated by Tulasne in 1949 and since then cultured in he absence of penicillin, have kept the ability to synthesize the seven penicillin-binding proteins and the various DD- and LD-peptidase activities found in the parental bacteria and known to be involved in wall peptidoglycan metabolism. The stable L-forms,...

Seizures in human immunodeficiency virus (HIV) patients can be caused by a wide variety of opportunistic infections, and, especially in developing countries, tuberculosis (TB) should be high on the differential. In India, TB is the most common opportunistic infection in HIV and it can have several different central nervous system manifestations, including intracranial tuberculomas. In this case...

Neurological effects of Valeriana officinalis have been recognized for many years. In this study, the anticonvulsant activity of methanolic extract of the plant were investigated in mice. Picrotoxin with doses of 6 and 12.5 mg/kg were used for induction of seizures. The effects of different doses of methanolic extract of the plant on the variation of beginning time of seizures, the incidence of...

Multiple sclerosis (MS) patients are three to six times more likely to develop epilepsy compared to the rest of the population. Seizures are more common in patients with early onset or progressive forms of the disease and prognosticate rapid progression to disability and death. Gray matter atrophy, hippocampal lesions, interneuron loss, and elevated juxtacortical lesion burden have been identif...

Fifteen patients who experienced epileptic seizures while playing video games are described together with a review of 20 cases in the English literature. Nine of the 15 cases and all but two of the reported cases experienced their first seizure while playing video games. Two thirds of patients had idiopathic generalised epilepsy and mainly reported generalised tonic clonic seizures, but some ha...

As an acute model o f focal epi lepsy, the penicil l in focus has been wide ly ut i l ized since the initial r epo r t by Walker and J o h n s o n (1945) . However , the cellular mechanisms responsible for the epi leptogenic e f fec t o f penlci lhn remain poo r ly u n d e r s t o o d . A characterist ic fea ture o f penici l l ininduced epilept ic foci is the pa roxysma l depolar iz ing shift ...

Thyme with the scientific moniker of Thymus vulgaris has been used in traditional medicine for treatment respiratory and gastrointestinal disease. Its extract also adopted to treat epilepsy other central nervous system (CNS) disorders. To evaluate effect T. (TVE), experimental model memory impairment caused by seizures was performed rats. Seizures Wistar rats (200-250 g) were induced a challeng...

We report a 12-year-old girl with history of absence and generalized tonic-clonic seizures as well stereotyped, light-induced, hand-waving episodes (HWEs) (video 1). The latter were occasionally accompanied by eye fluttering. Notably, her maternal uncle had childhood-onset seizures. Video-EEG confirmed that HWEs epileptic in nature 2). She was started on fenfluramine addition to valproate parti...