Literature suggests that it is possible to design and implement pen-based computer interfaces that resemble the use of pen and paper. These interfaces appear to allow users freedom in expressing ideas and seem to be familiar and easy to use. Different ideas have been put forward concerning this type of interface, however despite the commonality of aims and problems faced, there does not appear ...

We examine the usability and performance of Tablet PC direct pen input with a conventional graphical user interface (GUI). We use a qualitative observational study design with 16 participants divided into 4 groups: 1 mouse group for a baseline control and 3 Tablet PC groups recruited according to their level of experience. The study uses a scripted scenario of realistic tasks and popular office...

OBJECTIVE To assess factors that might affect patient use of insulin pens. RESEARCH DESIGN AND METHODS Patients (n = 600: 300 using vial and syringe and 300 using pen) were recruited from national panels to participate in computer-assisted telephone interviews. Measures included: demographic characteristics; diabetes treatment and self-care factors; perceptions of pen convenience, clinical ef...

Oculab Tono-Pen tonometry was compared with Goldmann applanation tonometry in 82 eyes of 82 patients with normal corneas and in 54 eyes of 54 patients who had undergone penetrating keratoplasty and whose corneas did not preclude the use of Goldmann tonometer. We found that the intraocular pressure (IOP) in 48% of the eyes with normal corneas and in 57% after keratoplasty has different measureme...

Penclomedine, a highly substituted pyridine derivative, has been selected by the National Cancer Institute for evaluation as a potential anticancer agent based on antitumor activity observed in murine tumor models following i.v., p.o., and i.p. administration. We have developed a reverse-phase high performance liquid chromatography assay for PEN, and subsequently investigated murine pharmacokin...

the aim of this study was to evaluate the effects of three lighting programs on immune system and performance of broiler chickens. a total of 288 seven day-old male broiler chicks (ross-308) were randomly distributed between three treatments. each group was housed in the separated room with eight pen and 12-birds per pen. the management conditions were similar for all treatments throughout the ...

Penclomedine [3,5-dichloro-4,6-dimethoxy-2-(trichloromethyl)pyridine], an antitumor agent, is currently in Phase I clinical trials and is believed to be a prodrug. In these studies, cerebellar effects have been dose limiting. Previous studies identified 4-demethylpenclomedine (4-DM-PEN) as the major plasma metabolite in rodents and humans. 4-DM-PEN was demonstrated to be an antitumor-active met...

PCV-2 within- and between-pen transmission was quantified by estimating the daily transmission rate beta and the basic reproduction ratio (R(0)) using a stochastic SEIR (Susceptible, Exposed, Infectious, Removed) model fitted on experimental data. Within-pen transmission was quantified by using four groups of eight SPF (specific pathogen-free) pigs (four infected and four susceptible pigs havin...