The selection of sieving polymer for RNA fragments separation by capillary electrophoresis is imperative. We investigated the separation of RNA fragments ranged from 100 to 10,000 nt in polyethylene glycol (PEG) and polyethylene oxide (PEO) solutions with different molecular weight and different concentration. We found that the separation performance of the small RNA fragments (<1000 nt) was im...

Acute lymphoblastic leukemia (ALL) accounts for almost 4000 cases annually in the United States, approximately two thirds of which are in children and adolescents. Treatment results of ALL have improved considerably in the past decade, due to an optimal stratification of patients and a rational use of different antileukemic agents among which L-asparaginase (L-ASNase) plays a fundamental role. ...

Dopamine mimics the exceptional moisture-resistant adhesive properties of the amino acid, DOPA, found in adhesive proteins secreted by marine mussels. The catechol side chain of dopamine was functionalized with a nitro-group, and the effect of the electron withdrawing group modification on the cross-linking chemistry and bioadhesive properties of the adhesive moiety was evaluated. Both nitrodop...

a facile and simple method was proposed to control the size and shape of the mgo nano structures with high surface area in the presence of efficient and cheap templates like peg 200, peg 600, peg 4000 and sorbitol at low temperature within a little time. nano rods and nanoparticles have been achieved by applying these templates and altering other growth parameters. the products were characteriz...

Ibuprofen-polyethylene glycol (PEG) conjugates (PEG-Ibu) were prepared and their potential as a prolonged release system was investigated. Two PEG-Ibu conjugates were synthesized from Ibuprofen and PEG with two different molecular weights by esterification in the presence of DCC and DMAP. The PEG-Ibu conjugates were characterized by FT-IR, (1)H NMR, Mass spectroscopy and DSC analysis. The solub...

The trans-sialidase of Trypanosoma cruzi (TcTS) catalyzes the transfer of sialic acid from host glycoconjugates to terminal β-galactopyranosides in the mucins of the parasite. During infection, the enzyme is actively shed by the parasite to the bloodstream inducing hematological alterations. Lactitol prevents cell apoptosis caused by the TcTS, although it is rapidly eliminated from the circulat...

hospital for follow−up treatment after an intracerebral bleed on 5 February 2002. We placed a percutaneous endoscopic gastrostomy (PEG) on 5 March 2002 for enteral feeding. She developed frequent vomiting of the nutrients administered through the PEG tube 26 months after PEG placement. We tried gastric motility stimulant drugs, but these were ineffec− tive, and on 21 June 2004 we performed a di...

In Chile, small wastewater treatment plants (WWTPs) (treatment capacity of less than 4,800 m3/d) are normally not designed with consideration for the potential valorization generated sludge. For this reason, they generally operated at high solids residence times (SRT) (15 d) to promote decay biomass, promoting sludge production and reducing costs associated biomass management. Operation SRT imp...

In this paper, a linear relationship is proposed relating the natural logarithm of partition coefficient, ln K for protein partitioning in poly (ethylene glycol) (PEG)-phosphate aqueous two-phase system (ATPS) to the square of tie-line length (TLL(2)). This relationship provides good fits (r(2) > 0.98) to the partition of bovine serum albumin (BSA) in PEG (1450 g/mol, 2000 g/mol, 3350 g/mol, an...