BACKGROUND Low tidal volume (VT) during anesthesia minimizes lung injury but may be associated to a decrease in functional lung volume impairing lung mechanics and efficiency. Lung recruitment (RM) can restore lung volume but this may critically depend on the post-RM selected PEEP. This study was a randomized, two parallel arm, open study whose primary outcome was to compare the effects on driv...

UNLABELLED Atelectasis caused by general anesthesia is increased in morbidly obese patients. We have shown that application of positive end-expiratory pressure (PEEP) during the induction of anesthesia prevents atelectasis formation in nonobese patients. We therefore studied the efficacy of PEEP in morbidly obese patients to prevent atelectasis. Twenty-three adult morbidly obese patients (body ...

Introduction 234 million major surgical procedures are performed worldwide every year. It has been shown that a ventilator strategy with low tidal volume (VT), high positive endexpiratory pressure (PEEP) and recruitment maneuvers (RM)s compared to low VT and low PEEP without RM did not protect against postoperative pulmonary complications [1]. So far, no study has evaluated the biological impac...

AUTO–positive end-expiratory pressure (auto-PEEP) is well described in patients with expiratory airflow obstruction, including those who require one-lung ventilation. Unfortunately, detecting auto-PEEP with most anesthesia ventilators is difficult. We report an unusual presentation of auto-PEEP during one-lung ventilation in which a reliable method of confirming lung separation quickly directed...

We report the effect of pressure support ventilation (PSV) on auto-PEEP in a patient with asthma. The patient showed a high level of auto-PEEP during spontaneous breathing through a T-piece. PSV effectively decreased auto-PEEP and inspiratory muscle effort with increasing levels of PSV.

BACKGROUND Acute Respiratory Distress Syndrome (ARDS) results in collapse of alveolar units and loss of lung volume at the end of expiration. Mechanical ventilation is used to treat patients with ARDS or Acute Lung Injury (ALI), with the end objective being to increase the dynamic functional residual capacity (dFRC), and thus increasing overall functional residual capacity (FRC). Simple methods...

BACKGROUND Baroreflex allows to reduce sudden rises or falls of arterial pressure through parallel RR interval fluctuations induced by autonomic nervous system. During spontaneous breathing, the application of positive end-expiratory pressure (PEEP) may affect the autonomic nervous system, as suggested by changes in baroreflex efficiency and RR variability. During mechanical ventilation, some p...

BACKGROUND Positive end-expiratory pressure (PEEP) may reduce cardiac output and total hepatic blood flow after liver transplantation. Pulse pressure variation is useful in predicting the PEEP-induced decrease in cardiac output. The aim of the study was to examine the relationships between stroke volume variations (SVV) obtained with the Vigileo monitor (Edwards Lifesciences, Irvine, CA), and t...

BACKGROUND Intermittent positive pressure ventilation applied through a nasal mask has been shown to be useful in the treatment of chronic respiratory insufficiency. Pressure support ventilation is an assisted mode of ventilation which is being increasingly used. Invasive ventilation with intermittent positive pressure, with or without positive end expiratory pressure (PEEP), has been found to ...

INTRODUCTION Finding the probable governing pattern of PEEP and CVP changes is an area of interest for in-charge physicians and researchers. Therefore, the present study was designed with the aim of evaluating the relationship between the mentioned pressures. METHODS In this quasi-experimental study, patients under mechanical ventilation were evaluated with the aim of assessing the effect of ...