Higher levels of physical fitness or activity (PFA) have been shown to have beneficial effects on cognitive function and grey matter volumes in older adults. However, the relationship between PFA and the brain's white matter (WM) is not yet well established. Here, we aim to provide a comprehensive and systematic review of magnetic resonance imaging studies examining the effects of PFA on the WM...

PURPOSE To determine intraocular toxicity and efficacy of the lipid prodrug of foscarnet, 1-O-octadecyl-sn-glycerol-3-phosphonoformate (ODG-PFA), as a long-acting, nontoxic intravitreous injectable drug delivery system for cytomegalovirus (CMV) retinitis. METHODS ODG-PFA was synthesized by coupling the phosphonate residue of PFA to the 3 hydroxyl of 1-O-octadecyl-sn-glycerol and formulated as...

Building on the work of Schimmerling ([11]) and Steel ([17]), we show that the failure of square principle at a singular strong limit cardinal implies that there is a non-tame mouse. This is the first step towards getting a model of ADR + “Θ is regular” from PFA via the core model induction. One of the wholly grails of inner model program has been determining the exact consistency strength of f...

Introduction. This is a sequel to our article “Predicative foundations of arithmetic” (1995), referred to in the following as [PFA]; here we review and clarify what was accomplished in [PFA], present some improvements and extensions, and respond to several challenges. The classic challenge to a program of the sort exemplified by [PFA] was issued by Charles Parsons in a 1983 paper, subsequently ...

BACKGROUND Providing psychological first aid (PFA) is generally considered to be an important element in preliminary care of disaster victims. Using the best available scientific basis for courses and educational materials, the Belgian Red Cross-Flanders wants to ensure that its volunteers are trained in the best way possible. OBJECTIVE To identify effective PFA practices, by systematically r...

The classical interpolation-based Polar Format Algorithm (PFA) for spotlight synthetic aperture radar (SAR) results in numerous computation load, which, reduces processing speed and increase system complexity. To decrease computation load, this paper proposes a novel non-interpolation PFA algorithm for sensor flying along non-lineal flight trajectories, which are specially designed curves in co...

Smooth-pursuit adaptation (SPA) refers to the fact that pursuit gain in the early, still open-loop response phase of the pursuit eye movement can be adjusted based on experience. For instance, if the target moves initially at a constant velocity for ~100-200 ms and then steps to a higher velocity, subjects learn to up-regulate the pursuit gain associated with the initial target velocity (gain-i...

The effect of a dietary phytogenic feed additive (PFA) inclusion level in mucin monosaccharide composition, mucosal morphometry and mucus histochemistry along the broiler intestinal tract was studied. Cobb male broilers (n = 525) were allocated into five experimental treatments that, depending on the type of addition in the basal diet (BD), were labeled as follows: C (BD based on maize-soybean ...

To quantify gait bradykinesia during daily activity in patients with Parkinson's disease (PD), we measured movement-induced accelerations over more than 24h in 50 patients with PD and 17 age-matched normal controls, using a new device, the portable gait rhythmogram. Acceleration values induced by various movements, averaged each 10 min, exhibited a gamma distribution. The mean value of the dist...

This study attempts to answer the question of distinguishing appropriate intensity measure parameter for performance-based design or assessment, taking into account the efficiency aspect. The comprehensive comparative tables proposed in this paper could be an effective support in the decision making procedure for intensity measure selection, comprising most of the frequently utilized intensity ...