The periodontal ligament (PDL) is one of the connective tissues located between the tooth and bone. It is characterized by rapid turnover. Periodontal ligament fibroblasts (PDLFs) play major roles in the rapid turnover of the PDL. Microarray analysis of human PDLFs (HPDLFs) and human dermal fibroblasts (HDFs) demonstrated markedly high expression of chemokine (CXC motif) ligand 12 (CXCL12) in t...

PURPOSE Although pulsed dye laser (PDL) treatment of port-wine stain (PWS) has long been proven safe and effective, incomplete clearance of these vascular malformations can be problematic. In addition, advanced PWS with deeper coloration and tissue hypertrophy can be particularly difficult to treat because of the superficial dermal penetration of 585- to 595-nm light. The purpose of this study ...

BACKGROUND Cathepsin S is a cysteine protease, which is expressed in human periodontal ligament (PDL) cells under inflammatory and infectious conditions. This in vitro study was established to investigate the effect of cathepsin S on PDL cell wound closure. METHODS An in vitro wound healing assay was used to monitor wound closure in wounded PDL cell monolayers for 72 h in the presence and abs...

Although cells derived from periodontal ligament (PDL) tissue are reported to have stem cell-like activity and are speculated to play a crucial role for tissue healing and regeneration after injury or orthodontic treatment, mechanisms regulating their recruitment and activation remain unknown. Recently, stromal cell-derived factor 1α (SDF-1α) has been reported to be important for stem cell homi...

A finite element model is used to explore the stress-strain responses of the mandibular central incisor and its associated periodontal ligament (PDL) while opening the bite. The finite element model consisted of the mandibular teeth, the alveolar bone, and the PDL of the mandibular incisors. The clinical scenario was simulated by applying a force of 10 cN to the mandibular incisor in a crown-ro...

BACKGROUND AND OBJECTIVES Neither the pathogenesis of port wine stain (PWS) birthmarks nor tissue effects of pulsed dye laser (PDL) treatment of these lesions is fully understood. There are few published reports utilizing gene expression analysis in human PWS skin. We aim to compare gene expression in PWS before and after PDL, using DNA microarrays that represent most, if not all, human genes t...

The human dental follicle partially differentiates into the periodontal ligament (PDL), but their biological functions are different. The gene-expression profiles of the dental follicle and PDL were compared using the cDNA microarray technique. Microarray analysis identified 490 genes with a twofold or greater difference in expression, 365 and 125 of which were more abundant in the dental folli...

INTRODUCTION Following avulsion, the periodontal ligament (PDL) cells are at risk of necrosis. To achieve a favorable survival prognosis, the PDL cells must be kept viability. Therefore, immediate replantation is considered as the treatment of choice and in case it is not possible, storing the tooth in an appropriate storage media should be considered. Oral Rehydration Solution (ORS) is a gluco...

An investigation of the polarization dependent loss (PDL) of macrobending loss sensitive single fiber (1060XP) is presented theoretically and experimentally. The experimental results are in good agreement with the modeling outcomes. Through the comparison of experimental results of PDL between 1060XP fiber with coatings and bare 1060XP fiber, it is shown that the fiber coating has significant i...

The performance of coherent polarizationmultiplexed optical systems is evaluated in the presence of polarization-dependent loss (PDL) for linear and maximumlikelihood receivers and lumped noise at the receiver. The boundaries of PDL mitigation methods are discussed.