P renatal and postnatal exposure to persistent organochlorine pollutants, such as polychlorinated biphenyls (PCBs), has been implicated as a possible cause of impaired immune function in children. For example, studies have shown that children who have been exposed to PCBs and related compounds from their mothers' contaminated diets have reduced concentrations of immunoglobulins and increased fr...

Organochlorines are environmentally persistent contaminants that readily cross the placenta, posing a potential risk to the developing fetus. Evidence for neurodevelopmental effects at low levels of these compounds is growing, though few studies have focused on behavioral outcomes. The authors investigated the association between prenatal polychlorinated biphenyl (PCB) and p,p'-dichlorodiphenyl...

Dead and dying glaucous gulls (Larus hyperboreus) were collected on Bjørnøya in the Barents Sea in 2003, 2004 and 2005. Autopsies of the seabirds only explained a clear cause of death for three (14%) of the 21 birds. A total of 71% of the birds were emaciated. Liver and brain samples were analysed for organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), polybrominated diphenyl et...

Polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) were measured in blubber biopsy samples from 22 live-captured Steller sea lions (Eumetopias jubatus) that had just entered the Strait of Georgia, British Columbia, Canada, for their overwintering feeding season. ∑PBDE ranged from 50μgkg(-1) (lipid weight) in adult females to 3780μgkg(-1) in subadult individuals. ∑PCBs r...

Mean serum levels of polychlorinated biphenyls (PCBs) in U.S. population groups without occupational exposure to PCBs are usually between 4 and 8 ng/mL, with 95% of individuals having serum PCB measurements of less than 20. Subpopulations consuming fish taken from contaminated waters, such as Lake Michigan and near Triana, AL, have mean serum PCB levels several times those found in other genera...

High-efficiency transfection of genes, proteins, or drug compounds into cells without causing permanent damage is a prerequisite for many cell biology experiments. Here, we report a printed circuit board (PCB)-based electroporation device for high-throughput delivery of exogenous molecules into cells in an individually addressable manner. This device incorporates an array of 96 through-holes on...

Emission of unintentionally formed polychlorinated biphenyls (PCBs) from industrial thermal processes is a global issue. Because the production and use of technical PCB mixtures has been banned, industrial thermal processes have become increasingly important sources of PCBs. Among these processes, secondary copper smelting is an important PCB source in China. In the present study, the potential...

The peptides were examined by lH NMR, circular dichroism spectroscopy, and secondary ion mass spectrometry. The ‘H NMR data confirmed that in each case the bilin was attached through a single linkage, a thioether bond between the cysteinyl residue and the tetrapyrrole moiety. Comparison of the ’H NMR spectra of these peptides with those of appropriate model compounds showed that the thioether l...

Organochlorine compounds are known to be atmospherically transported to long distances from their original sources. To understand the influence of California's Sierra Nevada range on the air transport and subsequent distribution pattern of some of these residues within the range, we have chosen salmonid fish as an indicator species. Fish were collected from 10 locations throughout the northern ...

The aim of this study was to determine human prenatal and postnatal exposures to polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs), hydroxylated metabolites of PCBs (polychlorobiphenylols; OH-PCBs), and pentachlorophenol (PCP). The median PBDE fresh-weight concentrations in maternal and cord blood plasma and in breast milk were 24, 4.3, and 75 pg/g, respectively. The PCB ...