We investigate the long time behavior of the critical mass Patlak-Keller-Segel equation. This equation has a one parameter family of steady-state solutions ̺λ, λ > 0, with thick tails whose second moment is not bounded. We show that these steady state solutions are stable, and find basins of attraction for them using an entropy functional Hλ coming from the critical fast diffusion equation in R ...

Edward P. Debold, J. P. Schmitt, J. B. Patlak, S. E. Beck, J. R. Moore, J. G. Seidman, C. Seidman, and D. M. Warshaw Department of Molecular Physiology and Biophysics, University of Vermont, Burlington, Vermont; Institute of Pharmacology and Toxicology, University of Würzburg, Würzburg, Germany; Department of Physiology and Biophysics, Boston University School of Medicine, Boston; Department of...

BACKGROUND We evaluated the utility of L-3,4-dihydroxy-6-[18F]fluoro-phenylalanine ([18F]FDOPA) positron emission tomography (PET) as a method for assessing the severity of dopaminergic dysfunction in unilaterally 6-hydroxydopamine (6-OHDA)-lesioned rats by comparing it with quantitative biochemical, immunohistochemical, and behavioral measurements. METHODS Different doses of 6-OHDA (0, 7, 14...

09:00 09:25 Coffee and registration 09:25 09:30 Introduction 09:30 10:00 Quantification of the Renogram: Deconvolution and Patlak/Rutland Plot Prof Richard Lawson, Central Manchester Nuclear Medicine Centre, Manchester 10:00 10:30 Improving quantification via multi-modality imaging Prof Brian Hutton, University College London 10:30 11:00 Coffee, Posters and Exhibiton 11:00 11:20 Use of the CT S...

UNLABELLED To evaluate myocardial blood flow (MBF) and cardiac function with a single dose of (13)NH(3), electrocardiographically (ECG) gated PET acquisition was performed after a dynamic PET scan was obtained. Gated blood-pool (GBP) imaging with C(15)O PET was also performed to compare the left ventricular ejection fraction (LVEF) obtained using the 2 methods. METHODS Six healthy volunteers ...

AIMS Recent studies have demonstrated that chronic obstructive pulmonary disease (COPD) is associated with cardiovascular disease (CVD). However, the association between COPD and coronary microcirculatory dysfunction is unknown. We sought to assess whether myocardial perfusion reserve (MPR) is impaired in patients with COPD, even in the absence of regional myocardial ischaemia or infarction, by...