Primary central nervous system lymphoma (PCNSL) is an extranodal type of lymphoma, which treated with methotrexate (MTX)‑based induction therapy. Although PCNSL a hematological malignancy, patients may be at neurosurgery or hematology/oncology departments; however, the outcomes treatment have not been compared between these two departments. The present study 26 newly diagnosed that were Departm...

Patients with chronic lymphocytic leukemia or non-Hodgkin’s lymphoma are at risk of infectious diseases of respiratory system because of immunodeficiency. Occurrence of organizing pneumonia in leukemic patients is most commonly correlated with bone marrow transplant or treatment with antimitotic agents. There have been only four reported cases of organizing pneumonia related solitarily to leuke...

Background: Non-Hodgkin lymphoma (NHL) includes a wide range of diseases with different clinical and biological features. NHL is usually presented as localized or generalized lymphadenopathy. It has been suggested that the HLA class I and II are associated with susceptibility to NHL. Different ethnic groups have been found to have different HLA class I and II alleles which affect NHL. Objective...

Terminal deoxynucleotidyl transferase activity, immunologic membrane markers, and cytochemical reactivity were examined in blasts of 80 adults with acute leukemia. The study was interinstitutional and prospective so that some assessment could be made of the usefulness and practicality of these tests in the classification of adult acute leukemias. Initial classification as to the type of acute l...

Richter's transformation (RT) represents the development of high grade lymphoma, most commonly diffuse large B-cell lymphoma, in patients with chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL/SLL). CLL/SLL may convert also to Hodgkin's lymphoma, the so-called Hodgkin's variant of Richter transformation. Histopathological proof is needed to confirm a definitive diagnosis. Patients...

From December 2000 until 2010, the researchers at Royan Institute conducted a wide range of investigations on ovarian tissue cryopreservation with the intent to provide fertility preservation to cancer patients that were considered to be candidates for these services. In 2010, Royan Institute established the Royan Human Ovarian Tissue Bank as a subgroup of the Embryology Department. Since its i...

Non-Hodgkin lymphoma (NHL) and leukemia are among the most common cancers worldwide. While the treatment of NHL/leukemia of B-cell origin has much progressed with the introduction of targeted therapies, few treatment standards have been established for T-NHL/leukemia. As presentation in both B- and T-NHL/leukemia patients is often aggressive and as prognosis for relapsed disease is especially d...

Abstract Study question What is the current status of fertility preservation (FP) male cancer utilization, efficacy and safety in China what national trends could be observed? Summary answer In this report on FP over a 11-year period, data population trends, region development are analyzed. known already Cryopreservation sperm, standard option to preserve patient's fertility, very advantageous ...

Bone marrow biopsy (BMB) examination is the gold standard for staging of lymphoma which interpreted along with other clinical, laboratory and radiological investigations. This study aimed to evaluate various patterns BMB infiltration by lymphomas include Hodgkin Non usefulness compared bone aspiration (BMA). : In a period three years, there were 212 cases showed in marrow. We assessed periphera...

Abstract Chimeric antigen receptor T cells have revolutionized the treatment of hematological malignancies during past five years, boasting impressive response rates and durable remissions for patients who previously had no viable options. In this review, we provide a brief historical overview their development. We focus on practical aspects patient’s journey through unique toxicities current b...