The number of elderly patients seeking clinical treatment for memory problems will rise sharply in coming years as our population ages. These patients present a challenge for diagnosis and prognosis since cognitive problems in older patients can arise from many etiologies, some of which are curable. With the development of clinically available biomarkers for detecting Alzheimer's disease pathol...

Background: There is a paucity of information about the oral pathology related articles published in a pathology journal. This study aimed to audit the oral pathology related articles published in Iranian Journal of Pathology (Iran J Pathol)from 2006 to 2015. Methods: Bibliometric analysis of issues of Iran J Pathol from 2006 to 2015 was perf...

Background: The aim of the study was to evaluate radiographic features systemic sclerosis-associated interstitial lung disease. Patients and methods: 116 patients with disease (SSc-ILD) from 2010 2019 comprised our retrospective study. All were subject high resolution computed tomography (HRCT). ILD patterns classified into 7 as IIPs analyzed pathology. We chose two staging method semi-quantita...

CONTEXT In the normal course of activity, pathologists create and archive immense data sets of scientifically valuable information. Researchers need pathology-based data sets, annotated with clinical information and linked to archived tissues, to discover and validate new diagnostic tests and therapies. Pathology records can be used for research purposes (without obtaining informed patient cons...

BACKGROUND Systematic reviews have shown that, although well prepared, the Consensus Guidelines have failed to change clinical practice. In the healthcare district of Castelnovo né Monti (Reggio Emilia, Italy), it became necessary for the GPs and Clinical Pathologists to work together to jointly define laboratory profiles. METHODS Observational study with two cycles of retrospective audit on ...

introduction: evaluation of persistent vertigo in post infarct patients is very important as the management depends on whether the cause is purely of central origin or due to associated vestibular affliction.   case report: a patient with left sided dorsolateral medullary syndrome and persistent vestibular symptoms was evaluated. vestibular test battery showed abnormal smooth pursuit, bilateral...

Molecular pathological epidemiology (MPE) is a multidisciplinary and transdisciplinary study field, which has emerged as an integrated approach of molecular pathology and epidemiology, and investigates the relationship between exogenous and endogenous exposure factors, tumor molecular signatures, and tumor initiation, progression, and response to treatment. Molecular epidemiology broadly encomp...

Human cells contain deoxyribonucleic acid in mitochondria and nuclei. Human diseases may be caused by mutations in mitochondrial DNA, nuclear DNA or both. The volume of work performed in the diagnostic molecular pathology laboratory will continue to grow as more disease-related mutations are discovered. Many factors will influence the diagnostic molecular pathology laboratory in the 21st centur...

background: coeliac disease is triggered by ingestion of gluten-containing cereals in genetically susceptible subjects. the aim of the study was to analyze correlation between serum antiendomysial antibody and antiglidin antibody and the grade of pathology in small intestine mucosa in children with celiac disease. materials and methods: this cross-sectional analysis was carried out in a group o...

ampullary tumor is a rare cancer. these patients most commonly present with obstructive jaundice but sometimes disease appear with uncommon signs. this report is an example of such cases. our case is a 53 year old man who presented with recurrent fever and chills and iron deficiency anemia and has been misdiagnosed for two years. the proper diagnosis occurred when the patient showed abnormal li...