To the Editor: Although pathogenesis of allergic contact dermatitis (ACD) has been classically thought to be driven predominantly by Th1, its complex pathophysiology is now accepted include Th2, Th17, and Th22 pathways.1Dhingra N. Shemer A. Da Rosa J.C. et al.Molecular profiling skin identifies allergen-dependent differences in immune response.J Allergy Clin Immunol. 2014; 134: 362-372Abstract ...

these were similar between all groups.When comparisons were made between the groups, these areas showed statistically significant differences: 1) Practitioners who see more patients with EoE more frequently were more likely to perform testing for immediate hypersensitivities to aeroallergens and foods. 2) Practitioners who participate more often in workshops were less likely to perfrom patch te...

www.aafp.org/afp AMERICAN FAMILY PHYSICIAN 621 patient, such as allergen avoidance, medications, and, sometimes, immunotherapy (Table 2). For example, a patient with a specific pollen allergy may be instructed to increase medication use during the pollen season. Patients with an animal allergy may be instructed to use allergy or asthma medication before exposure. There are several types of spec...

BACKGROUND Characterization of opioid excretion in sweat is important for accurate interpretation of sweat tests in drug treatment, criminal justice, and workplace drug testing programs. METHODS Participants (n=20) received placebo, 3 low (60 mg/70 kg) or 3 high (120 mg/70 kg) codeine sulfate doses (used as a model for opioid excretion) within 1 week. Codeine and metabolites in sweat were col...

Delayed-type hypersensitivity reactions (DTHRs) after subcutaneous application of unfractionated heparins or low-molecular-weight heparins are not uncommon. Standard allergological testing usually includes intracutaneous skin tests and patch testing of different heparins, heparinoids, and thrombin inhibitors followed by subcutaneous and/or intravenous challenge with skin test-negative drugs. We...