Fluid mixing is a crucial and challenging process for microfluidic systems, which are widely used in biochemical processes. Because of their fast performance, active micromixers that use stirrer blades are considered for biological applications. In the present study, by using a robust and convenient Incompressible Smoothed Particle Hydrodynamics (ISPH) method, miscible mix...

Strong acoustic streaming can be generated inside a microchannel near sharp-edge structures. In this study, three Sharp-Edge Acoustic Streaming (SEAS) micromixers with multiple sharp edge patterns actuated by piezoelectric transducers are investigated. Direct Numerical Simulation (DNS) is used to numerically solve the multi-physics phenomenon involving acoustics, fluid dynamics and mass transfe...

Sperm motility analysis of aquatic model species is important yet challenging due to the small sample volume, necessity activate with water, and short duration motility. To achieve standardization sperm activation, microfluidic mixers have shown improved reproducibility over activation by hand, but challenges remain in optimizing simplifying use these microdevices for greater adoption. The devi...

This paper reports a multilayered, automated PDMS based microTAS for rapid, high-sensitivity and point-of-care insulin detection. Two generations of microTAS differing in their design complexity and insulin detection protocol were compared. The first generation microTAS includes one micropump, one micromixer and interdigitated electrodes to perform flow through impedance spectroscopy for insuli...

A novel microdevice for passively mixing liquid samples based on surface tension and a geometrical mixing chamber is presented. Due to the laminar flow regime on the microscale, mixing becomes difficult if not impossible. We present a micromixer where a constantly changing time dependent flow pattern inside a two sample liquid plug is created as the plug simply passes through the planar mixer c...