Recurrent, episodic conditions in medicine (paroxysmal disorders) have been seriously neglected in many ways. They require more adequate terminology, delineation of diagnostic criteria, appreciations of the conditions in all the different ethicobiopsychofamiliosociocultural contexts, and awareness of the need for management after adequate evaluation. This has led by necessity to the development...

UNLABELLED Bath-induced paroxysmal events in infants and children can be triggered by various etiologies, including cardiological, neurological, and metabolic causes. It is important to ascertain the underlying cause for such events as this significantly affects the child's management and prognosis. We present the case of a 19-month-old boy who presented with recurrent episodes of apnea, cyanos...

The risks of stroke or systemic embolism and major bleeding are considered similar between paroxysmal and sustained atrial fibrillation (AF), and warfarin has demonstrated superior efficacy to aspirin, irrespective of the AF type. However, with the advent of novel oral anticoagulants (NOACs) and antiplatelet agents, the optimal antithrombotic prophylaxis for paroxysmal AF remains unclear.We sea...

1 Fertleman CR, Ferrie CD, Aicardi J, et al. Paroxysmal extreme pain disorder (previously familial rectal pain syndrome). Neurology 2007; 69: 586–95. 2 Fertleman CR, Baker MD, Parker KA, et al. SCN9A mutations in paroxysmal extreme pain disorder: allelic variants underlie distinct channel defects and phenotypes. Neuron 2006; 52: 767–74. 3 Dib-Hajj S, Estacion M, Jarecki BW, et al. Paroxysmal ex...

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PURPOSE The aim of the present study was to define the atrial electrical substrate in patients with paroxysmal atrial fibrillation (AF) occurring in the absence of overt structural heart disease and to assess if electrophysiological parameters could predict AF recurrence after radiofrequency ablation in this population. METHODS AND RESULTS 45 consecutive patients (39 male, age 59 ± 10 years) ...

The value of video-electroencephalographic monitoring (EEG-VM) in evaluating patients with epileptic disorders constitutes a major research field. This study investigates the usefulness of inpatient long-term EEG-VM for pediatric neurology patients under four headings: pre-surgical evaluation; seizure classification; epileptic seizure and non-epileptic paroxysmal event differentiation; and anti...