background: parkinson’s disease (pd) is a progressive neurodegenerative disorder causing motor and non‑motor symptoms. the latter are common and include autonomic dysfunction, cognitive impairment, and sleep difficulties. many of the non‑motor aspects of pd such as sleep disturbance are more common and significantly affect the day‑to‑day activities of patients and their quality of life. the mos...

The objective of this study was to determine whether hypothyroidism is more common in Parkinson patients than in a control group without Parkinson, as suggested in the past. We performed a retrospective file review of all admissions to the geriatric ward during a 1-year period. Concentrations of thyroid stimulating hormone (TSH) and thyroxine (T4) from 92 Parkinson patients were compared with t...

BACKGROUND Most prognostic studies on Parkinson disease have been hospital based or have applied register-based case-finding methods. Potential under-representation of mild cases may have given biased results. OBJECTIVE To evaluate whether Parkinson disease is associated with an increased risk of dementia and death. DESIGN Population-based cohort study. Parkinson disease and dementia were a...

The effects of the inflammatory mediators involved in systemic lupus erythematous (SLE) on subsequent Parkinson disease have been reported, but no relevant studies have focused on the association between the 2 diseases. This nationwide population-based study evaluated the risk of Parkinson disease in patients with SLE.We identified 12,817 patients in the Taiwan National Health Insurance databas...

A Doença de Parkinson (DP) tem como fisiopatologia a disfunção neurotransmissores, principalmente perda progressiva dos neurônios dopaminérgicos da porção compacta substância negra, que exerce importante função no controle motor do indivíduo. O projeto extensão “Assistência Fisioterapêutica em Grupo para Indivíduos com Parkinson” (AGruPar) propósito realizar atendimentos grupo indivíduos diagno...

Introduction: studies have suggested that free radicals-induced neurodegeneration is one of the many studies of Parkinson Disease (PD). Quercetin as a natural polyphenol has been regarded as a significant player in altering the progression of neurodegenerative diseases by protecting from damages caused by free radicals. Owing to its poor water solubility, preparation of its oral formulation is ...

Background Parkinson disease is the second most common neurodegenerative disease and the proportion of people suffering from parkinsonism and Parkinson disease is expected to increase as populations age. Few studies investigated the incidence of parkinsonism and Parkinson disease in the general population, and most of these were based on clinical data only. Objective To estimate the incidence o...