Primary hyperparathyroidism in childhood is rare. Anspach and Clifton found only 12 cases up to 1939 and since then a few cases in children have been reported by Pugh (1946), Tsumori, Jensen, Hunnicutt, Foreman and Kinsell (1955), Crawford, Stefanelli and Alvarez (1956); these have in general, shown the changes typical of the adult. The case described here is thought worthy of notice, not only ...

Objective: Parathyroid adenomas are the most common cause of primary hyperparathyroidism. Biological studies have shown that parathyroid adenomas are monoclonal proliferations. Up to date, five cell types have been identified in normal parathyroid tissues; chief cells, vacuolated chief cells, dark chief cells, oxyphil cells and transitional oxyphil cells. Most parathyroid adenomas are predomina...

The parathyroid gland of Rana tigrina is composed of closely packed epithelial cells which are arranged in whorls. A difference in the density of the parathyroída1 cells has been noticed. Cells in the center of the gland are packed compactly possessing elongated nuclei and denser cytoplasm. The cells at periphery of the gland are loosely arrenged having lightly stained cytoplasm and large spher...

HYPOTHESIS Parathyroid scanning, based on simultaneous recording of technetium Tc 99m sestamibi and iodine 123 images, is able to identify patients with multiple parathyroid gland disease and is a safe imaging technique for unilateral parathyroid surgery. DESIGN Scintigraphic criteria of eligibility for unilateral surgery were prospectively tested against findings of conventional bilateral su...

PARATHYROID CARCINOMA IS a rare endocrine malignancy. It accounts for <1% of cases of sporadic primary hyperparathyroidism (PHPT) and is usually associated with more severe clinical manifestations than its much more common benign counterpart, parathyroid adenoma. Its course is typically indolent but progressive. The diagnosis of malignancy is often made only when local recurrence or metastases ...

Ultrastructural changes of the parathyroid glands of pinealectomized golden hamsters were investigated. The main changes in the parathyroid glands 1 hour and 1 day after pinealectomy compared with the control and sham-operated groups were an increase of the Golgi complexes, cisternae of the granular endoplasmic reticulum and large vacuolar bodies. In addition, many chief cells contained numerou...

The concomitant appearance of a sublingual thyroid and primary hyperparathyroidism due to parathyroid mediastinal adenoma is not common. This co-occurrence can lead to a misdiagnosis by morphological imaging methods alone. This case emphasizes the role of 99mTc-MIBI scintigraphy in the detection of parathyroid ectopic adenoma in a patient with an ectopic thyroid gland. This more accurate locati...

A 54-year-old woman with end-stage renal disease and on haemodialysis for 4 years developed severe secondary hyperparathyroidism and was operated upon. The two upper and the largest lower parathyroid glands were resected. The right lower gland was dissected from the lower pole of the thyroid and, by gently pulling upwards, the lateral walls were dissected using electrocautery. The lower aspect ...

BACKGROUND/AIM Primary hyperparathyroidism (pHPT) is an endocrine disease with the third highest incidence of all endocrine disorders after diabetes mellitus and hyperthyroidism. pHPT is typically caused by a solitary parathyroid adenoma, less frequently by multiple parathyroid gland disease (MGD) and rarely by parathyroid carcinoma. Secondary hyperparatyroidism (sHPT) is a common complication ...

conclusions io-pth levels should become normal or to drop by at least 80% during successful parathyroidectomy. persistent elevations of io-pth after resection of an abnormal gland dictate the need for bilateral exploration. background we hypothesized that io-pth levels would decline to normal or near normal after successful parathyroidectomy. objectives evaluate efficacy and predictive factor o...