BACKGROUND Opisthorchis felineus, O. viverrini, and Clonorchis sinensis (family Opisthorchiidae) are parasitic flatworms that pose a serious threat to humans in some countries and cause opisthorchiasis/clonorchiasis. Chronic disease may lead to a risk of carcinogenesis in the biliary ducts. MicroRNAs (miRNAs) are small noncoding RNAs that control gene expression at post-transcriptional level an...

Schistosomiasis, caused by parasitic flatworms of the genus Schistosoma, is a neglected tropical disease affecting hundreds of millions globally. Praziquantel (PZQ), the only drug currently available for treatment and control, is largely ineffective against juvenile worms, and reports of PZQ resistance lend added urgency to the need for development of new therapeutics. Ion channels, which under...

BACKGROUND Lymphatic filariasis is caused by the parasitic worms Wuchereria bancrofti, Brugia malayi or B. timori, which are transmitted via the bites from infected mosquitoes. Once in the human body, the parasites develop into adult worms in the lymphatic vessels, causing severe damage and swelling of the affected tissues. According to the World Health Organization, over 1.2 billion people in ...

The study is aimed at development of physicochemical parameters and to investigate the active principle present in Tridax procumbens Linn. Tridax procumbens Linn. (Asteraceae) commonly known as Coat Buttons is an important plant used against various disorders in indigenous system of medicine such as Wound-Healing, Hepatoprotective, Anti-Inflammatory, Anti-diabetic and Immunomodulatory activitie...

The study investigated direct anthelmintic effects of sesquiterpene lactones (SL)-containing extracts from forage chicory against free-living and parasitic stages of Ostertagia ostertagi. Freeze-dried leaves from chicory cultivars 'Spadona' and 'Puna II' were extracted using methanol/water. Total SL were further fractionated by solid-phase extraction and resulting extracts were characterised by...

JONES, H.I., 2003 (19:xii): Parasitic worms in reptiles from Tasmania and the islands of Bass Strait. Papers and Proceedings of the Royal Society of Tasmania 137: 7-12. ISSN 0080-4703. Department of Microbiology, University of Western Australia, Nedlands, Western Australia 6009, Australia. The endoparasitic worms in reptiles from Tasmania and the islands of Bass Strait were recorded from dissec...

Background. Malaria is prevalent in sub-Saharan Africa, where other concomitant parasitic infections, including intestinal helminths, are common. However, little is known about how concurrent infections affect the expression or pathogenesis of each other. This study aimed to document the prevalence rates of malaria and intestinal helminths individually and as coinfection among asymptomatic chil...

Given their ubiquitous nature, it is surprising that more oligochaete annelid worms (Annelida: Clitellata) have not adopted an endoparasitic lifestyle. Exceptions, however, are the understudied members of the genus Dero (Allodero) that parasitize the ureters of tree frogs and toads. This study experimentally explores the life cycle and host specificity of Allodero hylae, the worm's use of chemi...

The Cambrian radiation is characterized by the emergence of diverse bilaterian animal phyla and establishment complex marine ecosystems. Guanshan Biota records an unusual ecological transition from trilobite- to brachiopod-dominated communities during Stage 4. This community accompanied direct evidence in situ biological interactions such as durophagous predation kleptoparasitism. Here we descr...

Poverty and poor sanitation in sub-Saharan Africa are the main reasons for parasitic infection prevalence. Medicinal herbs have been sources of natural cheaper remedies treatment many infections, including intestinal parasites. The study aimed to document medicinal used treating worm infections Ibadan metropolis through an ethnobotanical survey. three traditional herb markets, Oje, Oja Oba Iwo ...