COVID-19 and cosmetic skin-fillers are two prevalent topics of today’s medicine, yet their interaction is not sufficiently studied. This article based on a clinico-morphological case where the patient, 37-year-old female, visited clinic with complaints painless palpable subcutaneous pathologic nodular lesions at site collagen filler injection after severe acute respiratory syndrome coronavirus ...

<p class="abstract">Pityriasis rubra pilaris (PRP) are a group of clinically similar papulo squamous dermatoses which present with erythematous, hyperkeratotic perifollicular papules tend to coalesce form plaques and may progress erythroderma. We report case 46-year-old female patient who came chief complaint itching burning sensation scaly patches on extremities since one year. On dermat...

Sir, A thirty-year-old male received influenza vaccination in the upper arm. Several days later, erythema appeared on vaccinated site and spread to trunk extremities. He had no family history of psoriasis. was treated with a topical corticosteroid for three months, which yielded effects and, thus, he referred our hospital. physical examination revealed numerous erythematous, scaly macules scatt...

Introduction: Palmoplantar keratodermas (PPK) constitute a clinically and genetically complex group of cornification disorders characterized by defective epidermal differentiation leading to marked palmoplantar hyperkeratosis. Classically, have been categorised as hereditary acquired forms. Case Presentation: A 12-year-old male patient presented our dermatology outpatient department with diffus...

Punctate palmoplantar keratoderma (PPPK) is a rare entity with an estimated prevalence rate of 1.17/100,000. PPPK usually presents with bilateral asymptomatic, tiny, hyperkeratotic punctate papules and plaques on the palmoplantar surface. Among the PPPK varieties, the linear presentation is much rarer, and so far there have been only 3 case reports. Here, we report the case of a 27-year-old fem...

Keratinocyte growth factor (KGF) is a member of the fibroblast growth factor (FGF) family (hence the alternative designation FGF-7). It is produced by stromal cells, but acts as a mitogen for epithelial cells. We examined the effects of topically applied KGF on healing of wounds in a porcine model. In partial-thickness wounds, KGF stimulated the rate of reepithelialization (p < 0.0002), associa...

OLP is a chronic inflammatory disease of unknown etiology that may develop into squamous-cell carcinoma. Cytokeratins, which are important components of the cytoskeleton, are excellent epithelial differentiation markers used to study neoplastic and inflammatory diseases. To study the profile of cytokeratins in OLP and their possible association with dysplastic alterations, monoclonal antibodies...

The angiogenic cytokine vascular endothelial growth factor (VEGF)-A plays a central role in both wound healing and tumor growth. In the skin, epidermal keratinocytes are a major source of this growth factor. To study the contribution of keratinocyte-derived VEGF-A to these angiogenesisdependent processes, we generated mice in which this cytokine was inactivated specifically in keratin 5-express...