نتایج جستجو برای: paracetamol clofenac

تعداد نتایج: 5327  

2014
Anne M. C. M. Doedée Greet J. Boland Jeroen L. A. Pennings Arja de Klerk Guy A. M. Berbers Fiona R. M. van der Klis Hester E. de Melker Henk van Loveren Riny Janssen

UNLABELLED Worldwide, paracetamol is administered as a remedy for complaints that occur after vaccination. Recently published results indicate that paracetamol inhibits the vaccination response in infants when given prior to vaccination. The goal of this study was to establish whether paracetamol exerts similar effects in young adults. In addition, the effect of timing of paracetamol intake was...

Journal: :Postgraduate medical journal 2000
I Stephenson J M Nightingale

Paracetamol is a widely consumed antipyretic and analgesic agent used either in combination or as a single agent. The general safety of paracetamol in therapeutic dosage has allowed it to become a freely available over-the-counter preparation. A safety evaluation of nonnarcotic analgesics in therapeutic doses ranked paracetamol as among the safest in their study. Most patients are not asked or ...

Journal: :Annals of the rheumatic diseases 2004
F Boureau H Schneid N Zeghari R Wall P Bourgeois

OBJECTIVE To compare the analgesic efficacy of single and multiple doses of ibuprofen with that of paracetamol in patients with knee or hip osteoarthritis (IPSO study). METHOD 222 patients were randomised in a double blind, multicentre study-156 (70%) had a painful knee joint and 66 (30%) a painful hip joint. The main efficacy criterion was pain intensity assessment after a single dose (ibupr...

Journal: :American journal of therapeutics 2000
R C Dart E K Kuffner B H Rumack

An unexpected clinical question has emerged in the treatment of pain or fever in the alcoholic patient: Is paracetamol a safe medication for the alcoholic patient? After decades of use in a variety of patients, sporadic reports suggest a relationship between liver injury and the use of paracetamol by alcoholic patients. We performed a systematic review of the medical literature to answer the qu...

Journal: :International journal of stroke : official journal of the International Stroke Society 2015
Inger R de Ridder Frank Jan de Jong Heleen M den Hertog Hester F Lingsma H Maarten A van Gemert A H C M L Tobien Schreuder Annemieke Ruitenberg E Lisette Maasland Ritu Saxena Peter Oomes Jordie van Tuijl Peter J Koudstaal L Jaap Kappelle Ale Algra H Bart van der Worp Diederik W J Dippel

RATIONALE In the first hours after stroke onset, subfebrile temperatures and fever have been associated with poor functional outcome. In the first Paracetamol (Acetaminophen) in Stroke trial, a randomized clinical trial of 1400 patients with acute stroke, patients who were treated with high-dose paracetamol showed more improvement on the modified Rankin Scale at three-months than patients treat...

2012
Roderick Clark Judith E Fisher Ingrid S Sketris Grace M Johnston

BACKGROUND Paracetamol (acetaminophen) is generally considered a safe medication, but is associated with hepatotoxicity at doses above doses of 4.0 g/day, and even below this daily dose in certain populations. METHODS The Nova Scotia Prescription Monitoring Program (NSPMP) in the Canadian province of Nova Scotia is a legislated organization that collects dispensing information on all out-of-h...

Journal: :Nigerian journal of clinical practice 2015
S S Unal M Aksoy A Ahiskalioglu A F Erdem S Adanur

AIM We investigated the efficacy of intravenous (IV) preemptive paracetamol on postoperative total fentanyl consumption and fentanyl-related side effects in patients undergoing open nephrectomy. MATERIALS AND METHODS A total of 60 patients scheduled for elective open nephrectomy under general anesthesia were included. All patients received Patient-controlled IV analgesia with fentanyl postope...

Journal: :iranian journal of pharmacology and therapeutics 0
ayodele oluseyi kolawole mary t. olaleye joshua o. ajele

paracetamol (acetaminophen, pcm) is a widely used over-the-counter analgesic and antipyretic drug. intake of a large dose of pcm may result in severe hepatic necrosis. oxidative stress is mediated by oxidative capacities of the pcm metabolite (n-acetyl-para-benzo quinoneimine, napqi), which covalently binds to proteins and other macromolecules to cause cellular damage. at low doses, napqi is co...

Journal: :Indian journal of experimental biology 2001
S Emmanuel T Amalraj S Ignacimuthu

Effect of coumestans isolated form the leaves of W. calendulacea was evaluated in paracetamol induced liver damage. The increased serum enzyme levels (lactate dehydrogenase, alanine and aspartate transaminase and alkaline phophatase) by paracetamol induction were significantly lowered due to coumestans treatment. Results of this study revealed that coumestans of W. calendulacea afforded a signi...

Journal: :BMJ 1997
A L Jones P C Hayes A T Proudfoot J A Vale L F Prescott E P Krenzelok

Paracetamol is commonly used for self poisoning, and the costs of treating the resulting liver failure in the few who develop it are high. The morbidity could be avoided by adding methionine to paracetamol tablets, but this would mean that the millions of people who take paracetamol responsibly would have to take methionine unnecessarily. Alison Jones and colleagues and Edward Krenzelok debate ...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید