The problem of ulnar drift in the rheumatoid hand has interested rheumatologists and hand surgeons for many years and almost as many theories as to cause have been postulated as there are structures in the vicinity of the joints concerned. To present yet another, without necessarily invalidating the rest, can be supported on the grounds that the metacarpophalangeal joints are extremely complica...

Pc3 geomagnetic ®eld ̄uctuations detected at low latitude (L'Aquila, Italy) during the passage of a high velocity solar wind stream, characterized by variable interplanetary magnetic ®eld conditions, are analyzed. Higher frequency resonant ̄uctuations and lower frequency phenomena are simultaneously observed; the intermittent appearance and the variable frequency of the longer period modes can ...

The nails are affected by several dermatological and systemic diseases, and it is uncommon to find an isolated nail abnormalities. However, there are some diseases, in which the nails are affected primarily and similarly there are syndromes in which the nails affection is one of its major components. Some medical conditions in which there is a link to the nails are known eponymously (Tabl. I). ...

Onset of type I keratin 17 (K17) synthesis marks the adoption of an appendageal fate within embryonic ectoderm, and its expression persists in specific cell types within mature hair, glands, and nail. We report that K17 null mice develop severe alopecia during the first week postbirth, correlating with hair fragility, alterations in follicular histology, and apoptosis in matrix cells. These alt...

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Pachyonychia congenita (PC) is a rare genodermatosis which may be associated with painful, focal hyperkeratosis on the soles. Plantar sweating at high ambient temperatures increases the blistering of the callosities. We report three patients with PC who had great problems in walking, especially during summer time. They were treated with intracutaneous plantar injections of botulinum toxin type ...