T cell-mediated allergy to Ni(++) is one of the most common forms of allergic contact dermatitis, but how the T-cell receptor (TCR) recognizes Ni(++) is unknown. We studied a TCR from an allergic patient that recognizes Ni(++) bound to the MHCII molecule DR52c containing an unknown self-peptide. We identified mimotope peptides that can replace both the self-peptide and Ni(++) in this ligand. Th...

An investigation was carried out on snake gourd at the research farm of Department Horticulture, Bangabandhu Sheikh Mujibur Rahman Agricultural University (BSMRAU), Bangladesh during March to June 2019. Significant heterosis observed for most characters studied find high heterotic combination better hybrids. Both positive and negative were found different F1 hybrids over parents. The best paren...

BACKGROUND Polymorphisms at cleavage sites (CS) can influence Gag and Pol proteins processing by the viral protease (PR), restore viral fitness and influence the virological outcome of specific antiretroviral drugs. However, data of HIV-1 variant-associated CS variability is scarce. METHODS In this descriptive research, we examine the effect of HIV-1 variants on CS conservation using all 9,02...

BACKGROUND: Various treatment modalities are available to improve esthetics of fluorosed teeth based on its severity. AIM: The aim the study was evaluate clinical performance different minimal invasive protocols mild moderate teeth. METHODS AND MATERIALS: Before interventions, tooth color coordinates L, a and b were recorded for 160 by Vita Easyshade V. Participants randomly allocated in eight ...

The immunoreactivity of seven peptides synthesized from Schistosoma mansoni proteins, was evaluated by dot-blot and ELISA assays using two different sensitization methodologies. The best results were obtained on wells of the Costar 3590 microplates coated with peptides P1, P2, P3, P6, and P7 using conventional methodology. The signals increased considerably (p < 0.0003) on wells sensitized with...

Combining ability analysis provides useful information for the selection of parents, in breeding program cucumber at Can tho, VietNam, as well related to nature and extent gene activities involved. Cucumberimprovement involves strategies enhance yieldpotential quality cucumber. Targeting improvement new varieties plants, combining abilities genetic parameters 12 traits estimated from full diall...

We present the modification of the outer protein shell of cowpea chlorotic mottle virus (CCMV) with linear and strained alkyne groups. These functionalized protein capsids constitute valuable platforms for post-functionalization via click chemistry. After modification, the integrity of the capsid and the reversible disassembly behavior are preserved.