Many workers have over many years tried to find a reliable method of detecting damage to the blood supply of the femoral head soon after fracture of the neck of the femur. Up to now the most promising method has been that in which a radioactive isotope is given intravenously and the amount of it appearing in the femoral head and trochanter is measured. In 1950 Tucker published a preliminary rep...

gC1qR is an ubiquitously expressed cell protein that interacts with the globular heads of C1q (gC1q) and many other ligands. In this study, the 7.8-kilobase pair (kb) human gC1qR/p32 (C1qBP) gene was cloned and found to consist of 6 exons and 5 introns. Analysis of a 1.3-kb DNA fragment at the 5'-flanking region of this gene revealed the presence of multiple TATA, CCAAT, and Sp1 binding sites. ...

By SHIRLEY EBBE,#{176} MARIO BALDINI AND JANET DONOVAN T HE ABILITY of platelets to survive in the circulation appears to be their most labile property. Platelets may function normally in blood coagulation in the presence of damage severe enough to prevent their circulation when transfused to compatible recipients.1 After storage for 2 weeks, platelets still exhibit clot retraction,2 one of the...

By RICHARD I. WALKER, J. C. HERION AND J. G. PALMER C URRENT EVIDENCE indicates that isotopic labeling of deoxyribonucleic acid ( DNA ) results from synthesis during mitotic interphas&5 and that acquired label is retained until cell death and degradation occur.”5 2 The validity of using inorganic radiophosphorus ( p:oi ) as a leukocyte DNA label rests on these findings. Leukocyte kinetics have ...

Lactobacillus helveticus CNRZ 892 contains a surface layer (S-layer) composed of protein monomers of 43 kDa organized in regular arrays. The gene encoding this protein (slpH) has been cloned in Escherichia coli and sequenced. slpH consists of 440 codons and is preceded by a ribosome-binding site (RBS) and followed by a putative rho-independent terminator. Indeed, Northern analysis revealed that...

E BULK OF DATA initially accumulated regarding the lymphocyte tended to indicate that its life span was relatively short. Thus, Minot and Isaacs,’ in 1925, transfused blood from a patient with chronic lymphocytic leukemia into a patient with lymphosarcoma. The recipient’s blood showed an elevated lymphocyte count for 35 minutes before returning to normal. Yoffey,2 in 1935, showed that in the do...