In our recent systematic review in Obstetrics and Gynecology International of the association between FGM/C and obstetric harm we concluded that FGM/C significantly increases the risk of delivery complications. The findings were based on unadjusted effect estimates from both prospective and retrospective studies. To accommodate requests by critics, we aimed to validate these results through add...

We propose an approximate distribution for the gapped local score of a two sequence comparison. Our method stands on combining an adapted scoring scheme that includes the gaps and an approximate distribution of the ungapped local score of two independent sequences of i.i.d. random variables. The new scoring scheme is defined on h-tuples of the sequences, using the gapped global score. The influ...

INTRODUCTION We evaluated the progress in the self-perceived competence of medical students in a range of common clinical, practical and personal skills, in their final six months of training. METHODS The study was conducted on 65 final-year medical students undertaking their senior clerkship training at International Medical University, Malaysia. Questionnaire surveys were conducted at the b...

Asymptotic and exact conditional approaches have often been used for testing agreement between two raters with binary outcomes. The exact conditional approach is guaranteed to respect the test size as compared to the traditionally used asymptotic approach based on the standardized Cohen's kappa coefficient. An alternative to the conditional approach is an unconditional strategy which relaxes th...

Writers taking this approach are recognizable by this admit/ dismiss pattern. Yes, the sample size is small, but we are confident it includes the major points of view. Okay, the statistical tests were a fishing expedition, but our p value was significant. In The Reflection, the writer lays out the aspects of the research design that create uncertainty about the knowledge contribution, paying at...

P-values are useful statistical measures of evidence against a null hypothesis. In contrast to other statistical estimates, however, their sample-to-sample variability is usually not considered or estimated, and therefore not fully appreciated. Via a systematic study of log-scale p-value standard errors, bootstrap prediction bounds, and reproducibility probabilities for future replicate p-value...

the many honorifics bestowed on the articles in this historical series, it is doubtful that any have had applied the best—funny. The rhetorical zest and smiling outrage that Joseph Berkson brings to his puncturing of the quasi-religious precepts of traditional statistics in his classic article 1 recalls for me a public debate I witnessed in the 1980s between a highly respected statistician and ...

1 Neuropeptide RFRP inhibits the pacemaker activity of terminal nerve GnRH 2 neurons 3 4 Chie Umatani, Hideki Abe and Yoshitaka Oka 5 6 Department of Biological Sciences, Graduate School of Science, The University of 7 Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, JAPAN 8 9 Running head: RFRP-induced hyperpolarization of TN-GnRH neurons 10 11 Corresponding author: 12 Yoshitaka Oka 13 Departmen...