نتایج جستجو برای: p stat 1
تعداد نتایج: 3583417 فیلتر نتایج به سال:
BACKGROUND Rapid determination of blood electrolyte concentrations can help determine electrolyte status and delivery of effective volume of electrolyte solutions in field conditions. OBJECTIVE To evaluate reliability of the i-STAT, a point-of-care (POC) device, in measuring blood K(+), Na(+), and CI(-) concentrations in cattle. ANIMALS Ninety-eight cattle with various diseases. METHODS I...
Phosphorylation of transcription factor STAT-1 on Y701 regulates subcellular localization whereas phosphorylation of the transactivating domain at S727 enhances transcriptional activity. In this study, we investigate the impact of STAT-1 and the importance of transactivating domain phosphorylation on the induction of peptide-specific CTL in presence of the TLR9-dependent immune adjuvant IC31. S...
We present a calculation of the pion quark momentum fraction, $⟨x⟩$, and its third Mellin moment $⟨{x}^{2}⟩$. also obtain directly, for first time, $⟨x⟩$ $⟨{x}^{2}⟩$ kaon using local operators. use an ensemble two degenerate light, strange, charm (${N}_{f}=2+1+1$) maximally twisted mass fermions with clover improvement. The masses are chosen so that they reproduce about 260 MeV 530 MeV. lattice...
This Letter presents measurements of the polarization of the top quark in top-antitop quark pair events, using 4.7 fb(-1) of proton-proton collision data recorded with the ATLAS detector at the Large Hadron Collider at √s=7 TeV. Final states containing one or two isolated leptons (electrons or muons) and jets are considered. Two measurements of α(ℓ)P, the product of the leptonic spin-analyzin...
The CP -violating weak phase ϕs and the decay width difference ΔΓs between light heavy Bs0 mass eigenstates are measured with CMS detector at LHC in a sample of 48500 reconstructed Bs0→J/ψϕ(1020)→μ+μ−K+K− events. measurement is based on data corresponding to an integrated luminosity 96.4fb−1, collected proton-proton collisions s=13TeV 2017–2018. To extract values ΔΓs, time-dependent flavor-tagg...
Matrix metalloproteinase-9 (MMP-9) activity is implicated in pathogenesis of central nervous system tuberculosis (CNS-TB). IFN , a key cytokine in TB, usually inhibits MMP-9 secretion. Addition of IFN to conditioned media from M. tb-infected monocytes (CoMTB) resulted in a 7-fold increase in MMP-9 activity detected by gelatin zymography (P<0.01). In contrast, tissue inhibitor of metalloproteina...
To investigate whether the JAK-STAT (Janus kinase-signal transducers and activators of transcription) pathway participates in the regulation of APOBEC3G (Apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G) gene transcription and to study the molecular mechanisms of interferon resistance in patients with chronic hepatitis B (CHB), changes in APOBEC3G and STAT-1 expression levels...
Enterohaemorrhagic Escherichia coli (EHEC) O157:H7 inhibits interferon (IFN)-gamma-stimulated tyrosine phosphorylation of signal transducer and activator of transcription (STAT)-1 in epithelial cells. We determined the effects of probiotics on EHEC-mediated disruption of IFN-gamma-stimulated STAT-1 activation in epithelial cell lines. Confluent Intestine 407, HEp-2 and Caco-2 epithelial cells w...
OBJECTIVE Our aim was to determine if the expression pattern of CLP-1 in developing heart is consistent with its role in controlling RNA transcript elongation by transcriptional elongation factor b (P-TEFb) and if the inhibitory control exerted over P-TEFb by CLP-1 is released under hypertrophic conditions. METHODS We performed immunoblot and immunofluorescence analysis of CLP-1 and the P-TEF...
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