During the past several years, there has been a growing interest in the medical implications of free radicals. These chemical entities are common by-products of many oxidative biochemical reactions in the cell. Free radicals are essential to a number of normal biochemical and physiological processes. They are too reactive to be tolerated in living tissue, and aerobic organisms use sophisticated...

background & aim: applications of synthetic antioxidant in food have side effects. in present study, the antioxidant potential of morus alba leaves, as natural antioxidant, was screened with cupric ion reducing assay (cuprac assay) and inhibition of lipid peroxidation. the aim of this study was to determine the total antioxidant activity of morus alba leaves. martial & methods: the fir...

Oxidants are compounds capable of withdrawing electrons from target atoms or molecules, thus initiating chemical reactions. In biological systems, oxidative modifications are often related to structural, functional and regulatory changes. Partially reduced oxygen species, also known as oxygen-derived free radicals, represent the most important group of biologically relevant oxidants. Significan...

This study was designed to test the free radical theory of aging by using Drosophila melanogaster as a model system. Oxygen free radicals are generated by mitochondria during the process of normal oxidative metabolism. Age-specific measurements of oxygen consumption, heat production and anti-oxidant enzyme activity were obtained from two inbred lines of male flies, one selected for longevity an...

murraya koenigii l. (rutaceae), commonly known as curry leaf tree, closely associated with south india where the word “curry” originates from the tamil “kari” for spiced sauces. curry leaves are a rich source of carbazole alkaloids which possess various biological activities such as antitumor, antioxidant and anti-inflammatory. curry leaf has a potential role in the treatment of diabetes. reser...

results and conclusions the analysis of covariance revealed that catalase activity significantly decreased in the copenhagen football test group after the assessment compared to regular football exercises group. meanwhile, the glutathione reductase values significantly increased (p < 0.05). the increase in glutathione reductase values led to the protection of erythrocyte metabolism through the ...

Objective: Ionizing radiation produces free radicals which induce DNA damage and cell death. Origanum vulgare leaf extract (OVLE) is a natural compound and its capability of scavenging free radicals and its antioxidant activity have been demonstrated by many researchers. In this study, using micronucleus assay, radioprotective effect of OVLE against clastogenic and cytotoxic effect of gamma irr...

Treatment of Chinese hamster ovary and mouse hybridoma cells with Mega-H brand silica hydride, a marketed antioxidant, after photosensitization with singlet oxygen and hydroxyl/superoxide reactive oxygen species through the use of rose bengal diacetate and malachite green resulted in an effective method of reducing free radical activity by more than 96% against singlet oxygen species and more t...

It has become clear since the workshop that free radicals are implicated not only in the promotion phase of carcinogenesis but during initiation as well. Since the workshop, however, despite intriguing trapping studies with Superoxide disimilase. catalase, and Cu-DIPS [copper(II)(3,5-diisopropylsalicylate)2] and generation of OJ using xanthine oxidase, little substantive evidence has been obtai...

f t f ree radicals are a group of highly reactive chemical molecules that have one or more unaired electrons and can oxidatively modify bimolecules that they encounter.1 Reactive oxygen pecies (ROS) are free radicals that are derived rom the metabolism of oxygen. They are present n all aerobic organisms. ROS play an important ole in many physiologic functions such as phagoytosis, which is media...