We describe the management of two patients undergoing awake carotid surgery who developed signs of cerebral ischaemia following cross-clamping of the internal carotid artery. Administration of oxygen 100% with a close-fitting anaesthetic facemask reversed the neurological deficit, avoiding the need for insertion of an internal carotid artery shunt. Thus, the incidence of shunt insertion, which ...

Eleven healthy girls (mean(SD): age 12.1(0.6) years) completed three, 2-day conditions in a counterbalanced, crossover design. On day 1, participants either walked at 60(2)% peak oxygen uptake (energy deficit 1.55(0.20) MJ) (EX), restricted food energy intake (energy deficit 1.51(0.25) MJ) (ER) or rested (CON). On day 2, capillary blood samples were taken at pre-determined intervals throughout ...

The surface heat transfer efficiency of three heating media (water, and forced air with and without a water vapor-pressure deficit) was compared using four commodities: mango, papaya, grapefruit, and orange. Forced vapor-saturated-air (VFA), and water (HW) transferred heat most efficiently to the fruit surface. Thermal stress to the fruit was greatest during heating in VFA. Thermal diffusivity ...

Mitochondrial matrix cyclophilin D (CyPD) is known to promote development of the mitochondrial permeability transition (MPT). Kidney proximal tubule cells are especially prone to deleterious effects of mitochondrial damage because of their dependence on oxidative mitochondrial metabolism for ATP production. To clarify the role of CyPD and the MPT in proximal tubule injury during ischemia-reperf...

Eleven healthy girls (mean ± SD: age 12.1 ± 0.6 years) completed three 2-day conditions in a counterbalanced, crossover design. On day 1, participants either walked at 60 (2)% peak oxygen uptake (energy deficit 1.55[0.20] MJ), restricted food energy intake (energy deficit 1.51[0.25] MJ) or rested. On day 2, capillary blood samples were taken at predetermined intervals throughout the 6.5 hr post...

Oxygen-sensing and transduction in purposeful responses in cells and organisms is of great physiological and medical interest. All animals, including humans, encounter in their lifespan many situations in which oxygen availability might be insufficient, whether acutely or chronically, physiologically or pathologically. Therefore to trace at the molecular level the sequence of events or steps co...

Introduction: ischemic preconditioning is one of the most important mechanisms, responsible for the increased brain resistance after stroke. One of the most important candidates to ischemia preconditioning is intermittent normobaric hyperoxia. In this study, the effect of intermittent normobaric hyperoxia on the expression of UCP2 was investigated in a stroke model. Methods: Rats were divid...

(CeOy)0.67(Al2O3)0.33 (1.5<y<2) (CeAlOx) thin films were deposited on p-type Si ~100! substrates by the pulsed laser deposition method at 650 °C. The effect of oxygen pressure on structural and thus dielectric properties of the CeAlOx films was extensively investigated. The CeAlOx thin films turned from a mixture of crystalline CeO2 , Ce2O3 , and Al2O3 to the amorphous CeAlO3 as the deposition ...