The aim of this study was to investigate the hepatoprotective effects of resveratrol in alcoholic liver disease (ALD). Alcohol was administered to healthy female rats starting from 6% (v/v) and gradually increased to 20% (v/v) by the fifth week. After 16 weeks of intervention, liver enzymes (aspartate aminotransferase [AST] and alanine aminotransferase [ALT]) were analyzed using a chemistry ana...

BACKGROUND It has been reported that higher levels of oxidative stress and inflammation play a key role in the progression of hepatocellular carcinoma (HCC) after surgery. Coenzyme Q10 is an endogenous lipid-soluble antioxidant. To date, no intervention study has investigated coenzyme Q10 supplementation in HCC patients after surgery. The purpose of this study was to investigate oxidative stres...

BACKGROUND Alcohol consumption is prevalent amongst HIV positive population. Importantly, chronic alcohol use is reported to exacerbate HIV pathogenesis. Although alcohol is known to increase oxidative stress, especially in the liver, there is no clinical evidence that alcohol increases oxidative stress in HIV positive patients. The mechanism by which alcohol increases oxidative stress in HIV p...

OBJECTIVE The present study aims to investigate the effect of cadmium and arsenic through a controlled food chain on the activities of some oxidative enzymes (Sulphite oxidase SO, Aldehyde oxidase AO, Monoamine oxidase MO and Xanthine oxidase, XO) in the liver, kidney, testes, heart and brain of rats. MATERIALS AND METHODS Fish (the first trophic level) were exposed to both metals (singly and...

In comparison to other vital organs such as the liver, kidney and brain, the lung is at a greater risk of developing oxidative stress and oxidative injury as a result of its continuous exposure to higher oxygen tensions, to other sources of oxidative stress in the form of environmental pollutants, irritants and free radical-generating carcinogens, and of having a large epithelial surface area [...