INTRODUCTION Splenic metastasis from ovarian carcinoma generally presents as peritoneal spread with multiorgan involvement. Fewer than 30 cases of solitary parenchymal splenic metastasis from ovarian carcinoma have been published in the literature. The presentation is often asymptomatic. CASE PRESENTATION An increase in tumor marker CA-125 from 18.1 to 132.6 units/ml (normal < 35 units/ml) wa...

Objective: Ovarian carcinoma is a malignant tumor with the highest mortality of any cancer occurring in female reproductive system. Cytoreductive surgery main treatment for ovarian and has markedly improved. Mechanism: This article discusses evolution development cytoreductive (CRS), including classical standard cell reduction, visceral-peritoneal debulking (VPD) ultra-radical cytoreduction (UR...

AIM To investigate suppression of RNA interference (RNAi) on expression of c-myc of SKOV3 ovarian carcinoma cell line. MATERIALS AND METHODS The c-myc -siRNA was designed and synthesized, then transfected to SKOV3 ovarian carcinoma cell lines. The cell lines were divided into four groups, including the blank control group, the siRNA transfection group, the mock transfection group and the nega...

© 2012 The Authors. doi: 10.2340/00015555-1450 Journal Compilation © 2012 Acta Dermato-Venereologica. ISSN 0001-5555 Skin metastasis of ovarian carcinoma is rare (1). Some cases show umbilical metastasis, known as Sister Mary Joseph’s nodule (2). Other cutaneous metastases of ovarian carcinoma include pilomatricoma-like (3) and cauliflower-type (4) variants. Only one case of nodular cutaneous m...

Background: A 54 year female presented with distension of abdomen, and weight loss. Abdominal ultrasonography revealed Bilateral Ovarian carcinoma. Patient was operated and specimen received to the department of Pathology. The resected specimen showed two large ovarian masses, on cut open solid and cystic areas seen. Histologically tubular pattern of tumor tissue seen with no endometriotic (end...

The risk and severity of ovarian carcinoma, the leading cause of gynecologic malignancy death, are significantly elevated in postmenopausal women. Ovarian failure at menopause, associated with a reduction in estrogen secretion, results in an increase of the gonadotropic luteinizing hormone (LH) and follicle-stimulating hormone (FSH), suggesting a role for these hormones in facilitating the prog...

BACKGROUND AND OBJECTIVE Establishing ovarian cancer cell lines will benefit researches on biological characteristics of ovarian cancer stem cells and antitumor drugs. This study was to establish a human ovarian carcinoma cell line from peritoneal effusion, and explore its biological characteristics. METHODS Cells were isolated from peritoneal effusion of an ovarian carcinoma patient, purifie...

Purpose. To assess if there is a significant difference in enhancement of high grade serous carcinoma of the ovary compared with other ovarian malignancies on clinically performed contrast enhanced MRI studies. Methods. In this institutional-review-board-approved study, two radiologists reviewed contrast enhanced MRI scans in 37 patients with ovarian cancer. Readers measured the signal intensit...

A case of ovarian carcinoma and systemic amyloidosis in a 64 year old woman with nephrotic syndrome is reported. Immunohistochemical study of renal and rectal biopsy specimens revealed the presence of amyloidosis AA antigens, consistent with secondary amyloidosis. The absence of chronic inflammatory or infectious disease suggested the presence of a neoplasm. The gynaecological sonogram showed a...

Background: DNA polymerase &beta; (pol &beta;) is a key enzyme of base excision repair pathway. It is a 1-kb gene consisting of 14 exons. Its catalytic part lies between exon 8 and exon 14. Exon 12 has a role in deoxyribonucleotide triphosphate selection for nucleotide transferase activity. Methods: Genomic DNA was isolated from ovarian carcinoma samples. Single strand conformation polymorphism...