OBJECTIVE Assess age and sex differences in the association of obesity and other CVD risk factors with osteoarthritis (OA) in Southern California American Indian/Alaska Native (AIAN) adults. DESIGN Cross-sectional study. SETTING Southern California. PARTICIPANTS 6,299 AIAN adults aged 35+ years from health clinic system. MAIN OUTCOME MEASURES Osteoarthritis prevalence. RESULTS Age-adj...

Background and Objective: Osteoarthritis (OA) a common wear tear pathology of joints occurring among females. There is need exercises regimen known to be the most appropriate conventional treatment that stop progression degeneration. Pilates based are recommended for reduction pain strengthen peripheral muscles. The Objective was determine effects on physical function in women with knee OA.&#x0...

Osteoarthritis (OA) is a degenerative joint disease caused by variety of factors, which highly prevalent in the elderly population and mainly characterized articular cartilage degeneration surrounding bone regeneration, with clinical manifestations repeated swelling, pain, stiffness deformity at later stage. OA chronic that gives patients their relatives many life inconveniences economic pressu...

Objective(s): Previous study has indicated that triiodothyronine (T3) facilitated cartilage degeneration in osteoarthritis (OA). This study aimed to investigate the effects of T3 on angiogenesis-related factor expression in human osteoblasts of OA subchondral bone.Materials and Methods: The subchondral bone specimens were obtained from O...

OBJECTIVE(S) Osteoarthritis (OA) or degenerative joint disease is the commonest form of arthritis and can lead to joint pain, decrease in joint's range of motion, loss of function, and ultimately disability. Exercise is considered as one of the non-pharmacological treatments of OA. But the effects of exercise on knee joint cartilage remain ambiguous. The aim of the present study was to investig...

Osteoarthritis (OA) is one of the most common musculoskeletal diseases and highly prevalent in older people. Whilst management knee OA usually multidisciplinary, use comprehensive geriatric assessment (CGA) for this condition still limited. Given background, with systematic review, we summarized current literature regarding importance CGA people affected by OA. A search across several databases...

Total knee arthroplasty (TKA) is a common surgical intervention for older individuals with advanced knee osteoarthritis (OA). TKA has been repeatedly shown to reduce the chronic knee pain associated with OA and improve physical functioning. [1-4]. Regardless, studies have also shown that individuals with OA who undergo TKA continue to have reduced quadriceps strength compared to age-matched cou...

Arthritic diseases are a major cause of disability and morbidity, and cause an enormous burden for health and social care systems globally. Osteoarthritis (OA) is the most common form of arthritis. The key risk factors for the development of OA are age, obesity, joint trauma or instability. Metabolic and endocrine diseases can also contribute to the pathogenesis of OA. There is accumulating evi...

Osteoarthritis (OA) is a multifactorial disease characterized by gradual degradation of joint cartilage. This study aimed to quantify major pathogenetic factors during OA progression in human cartilage. Cartilage specimens were isolated from OA patients and scored 0-5 according to the Osteoarthritis Research Society International (OARSI) guidelines. Protein and gene expressions were measured by...