INTRODUCTION: The STR/ort strain of mouse, an inbred strain derived from STR/1N, has been reported to be an acceptable animal model for studying the development of osteoarthritis (OA) [1]. About 85% of all male mice spontaneously develop OA in the medial tibial plateau of the knee joint at 7-9 months of age. Importantly, histopathological changes in the lesions of the STR/ort mouse closely rese...

Building knowledge-based systems today usually entails constructing a new knowledge base from scratch. Even if several groups of researchers are working in the same general area, such as medicine or electronic diagnosis, each team must develop its own knowledge base from scratch. The cost of this duplication of effort has been high and will become prohibitive as we build larger and larger syste...

Im Artikel wird anhand der internationalen Diskussion über Lehrerausbildung und mithilfe des Ansatzes der Phänomenographie ein Konzept zur Integration von Schülerlaboren in die Informatiklehramtsbildung vorgestellt, um so die Praxisbezüge der ersten Phase der Lehrerausbildung zu stärken. Gleichzeitig werden Grundlagen gelegt, um durch einen ‚forschenden Blick„ auf Unterricht Kompetenzen zur Pla...

In 1979 oral rehydration therapy (ORT) using oral rehydration salts (ORS) solution became the cornerstone of the global effort, initiated by WHO, to reduce deaths of young children from diarrhoea, then estimated at 4.6 million annually (1). National programmes to control diarrhoeal diseases (CDD) were eventually developed in more than 110 countries. These gave priority to ensuring an adequate s...

I estimate a dynamic model in which a board of directors and a CEO interact to set the levels of CEO incentives and e¤ort. The intent is to understand the e¤ect that CEO incentives have on …rm value. In the model incentive levels are the result of CEO risk aversion, the cost of CEO e¤ort, the e¤ect of CEO e¤ort on …rm value, the volatility of shocks to …rm value, and the preference a board has ...

Purpose. To evaluate the relationship between macular microstructures and visual function in retinitis pigmentosa (RP). Method. Fourier domain optical coherence tomography (FD-OCT) and Goldmann perimetry were used to examine 100 eyes of 100 RP patients. The preserved photoreceptor outer segment (PROS) length was measured at the horizontal and vertical high definition line scans. The PROS area w...